UittrekselDiabetes as a chronic disease that cannot be cured calls for long term monitoring. Multiple researches have been carried out to achieve accurate noninvasive blood glucose monitoring. In this paper we theoretically and experimentally studied the feasibility and accuracy of noninvasive blood glucose monitoring with the optical coherence tomography (OCT) technique. Measurements on polystyrene microsphere solutions with dissolved glucose were carried out with an swept source OCT system. Physical averaging and wavelet filter denoising techniques were used to reduce speckles in the OCT images. Least squares regression with cross-validation was used to predict glucose concentrations in the samples. A root mean square error of 72.7663 mg/dL (4 mM) was achieved with a correlation coefficient of 0.9134 between reference and predicted values. By fitting with the Clarke error grid analysis, the prediction of glucose concentration by use of OCT shows a better sensitivity than specificity.
|Datum Prijs||15 sep 2015|
|Begeleider||Erwin Bente (Afstudeerdocent 1) & Par Dunias (Externe coach)|
Non-invasively measuring blood glucose by use of OCT
Li, W. (Auteur). 15 sep 2015