Validation of adaptive bone-remodeling simulation models

R. Huiskes

Onderzoeksoutput: Hoofdstuk in Boek/Rapport/CongresprocedureHoofdstukAcademicpeer review

13 Citaten (Scopus)
111 Downloads (Pure)


Using computer models based on Finite Element Analysis (FEA), Wolffs paradigm of mechanically-controlled adaptive bone remodeling can be simulated. These simulation models use empirical mathematical rules that describe the assumed relationships between local bone loads and bone mass. These models are particularly valuable for preclinical testing of orthopaedic implants, relative to their bone-maintaining capacities. In this chapter the question of validity of these models for these purposes is considered. Furthermore, an overview is presented of validation studies that were performed by the research group of the author.
Originele taal-2Engels
TitelBone research in biomechanics
Plaats van productieAmsterdam
UitgeverijIOS Press
Aantal pagina's228
ISBN van geprinte versie90-5199-327-7
StatusGepubliceerd - 1997

Publicatie series

NaamStudies in health technology and informatics
ISSN van geprinte versie0926-9630


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