Transport of guest molecules by unimolecular micelles evidenced in analytical ultracentrifugation experiments

M.V Rasa, M.A.R. Meier, U.S. Schubert

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

2 Citaten (Scopus)
1 Downloads (Pure)

Samenvatting

The ability of star-shaped, block copolymer-based unimolecular micelles to encapsulate and transport guest molecules was studied. Analytical ultracentrifugation studies clearly showed that methyl-orange guest molecules could be encapsulated and transported, together with unimolecular micelles consisting of 5-arm, star-shaped block copolymers with a poly(ethylene glycol) core and a poly(-caprolactone) corona. Sedimentation-velocity and equilibrium measurements were performed to determine the sedimentation coefficients, molar masses, and diffusion coefficients of the loaded, unimolecular micelles. It was observed that the transport of guest molecules by unimolecular micelles was a function of the molecular weight of the star-shaped block copolymers and therefore also of their size.
Originele taal-2Engels
Pagina's (van-tot)1429-1433
TijdschriftMacromolecular Rapid Communications
Volume28
Nummer van het tijdschrift13
DOI's
StatusGepubliceerd - 2007

Vingerafdruk Duik in de onderzoeksthema's van 'Transport of guest molecules by unimolecular micelles evidenced in analytical ultracentrifugation experiments'. Samen vormen ze een unieke vingerafdruk.

Citeer dit