The relative contributions of muscle deformation and ischaemia to pressure ulcer development

S. Loerakker, G.J. Strijkers, K. Nicolay, F.P.T. Baaijens, D.L. Bader, C.W.J. Oomens

Onderzoeksoutput: Hoofdstuk in Boek/Rapport/CongresprocedureHoofdstukAcademicpeer review


Sustained mechanical loading of soft tissues covering bony prominences may lead to degeneration of skeletal muscle tissue. This can result in a condition termed deep tissue injury (DTI), a severe kind of pressure ulcer that initiates in deep tissue layers, and progresses towards the skin. Previously, we have provided evidence that in a controlled animal model, deformation is the main trigger for damage within a 2 h loading period [1,2]. Recently, we also showed that ischemia and reperfusion may contribute to the damage process during prolonged loading [3]. In the present study, we investigated the relative effects of deformation, ischemia, and reperfusion on the temporal and spatial damage process of skeletal muscle tissue during a 6 h period using magnetic resonance imaging (MRI) techniques.
Originele taal-2Engels
TitelProceedings of the ASME summer bioengineering conference, pts A and B
Aantal pagina's2
StatusGepubliceerd - 2012
EvenementASME 2013 Summer Bioengineering Conference (SBC 2013) - Sunriver, Verenigde Staten van Amerika
Duur: 26 jun 201329 jun 2013


CongresASME 2013 Summer Bioengineering Conference (SBC 2013)
Verkorte titelSBC 2013
LandVerenigde Staten van Amerika
AnderASME 2013 Summer Bioengineering Conference (SBC 2013)
Internet adres

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