Tethered particle motion (TPM) characterizes binding types for lab-on-a-chip biosensing

E.W.A. Visser; L.J. IJzendoorn, van; M.W.J. Prins

Tethered particle motion (TPM) characterizes binding types for lab-on-a-chip biosensing

E.W.A. Visser, L.J. IJzendoorn, van, M.W.J. Prins

Onderzoeksoutput: Hoofdstuk in Boek/Rapport/Congresprocedure › Conferentiebijdrage › Academic › peer review

Samenvatting

We present a study on the application of tethered particle motion (TPM) for biosensing. Specifically, we investigate the dynamics of surface bound particles using TPM. In a model system, we demonstrate that particle binding to a sensor surface can be controlled via single tethers and via multiple tethers, and that the binding types can be quantified with TPM in an optical biosensing system.

Originele taal-2	Engels
Titel	18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
Uitgeverij	Royal Society of Chemistry
Pagina's	2303-2305
Aantal pagina's	3
ISBN van elektronische versie	9780979806476
Status	Gepubliceerd - 1 jan. 2014
Evenement	18th Intermational Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, Verenigde Staten van Amerika Duur: 26 okt. 2014 → 30 okt. 2014 Congresnummer: 18 http://www.microtasconferences.org/microtas2014/

Congres

Congres	18th Intermational Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
Verkorte titel	MicroTAS 2014
Land/Regio	Verenigde Staten van Amerika
Stad	San Antonio
Periode	26/10/14 → 30/10/14
Ander	µTAS 18th Int. Conf. on Miniaturized Systems for Chemistry and Life Sciences
Internet adres	http://www.microtasconferences.org/microtas2014/

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@inproceedings{a9eb7803428e432a9619b6652504b95e,

title = "Tethered particle motion (TPM) characterizes binding types for lab-on-a-chip biosensing",

abstract = "We present a study on the application of tethered particle motion (TPM) for biosensing. Specifically, we investigate the dynamics of surface bound particles using TPM. In a model system, we demonstrate that particle binding to a sensor surface can be controlled via single tethers and via multiple tethers, and that the binding types can be quantified with TPM in an optical biosensing system.",

keywords = "Biosensing, Bond discrimination, Bond dynamics, Particles, Tethered particle motion",

author = "E.W.A. Visser and {IJzendoorn, van}, L.J. and M.W.J. Prins",

year = "2014",

month = jan,

day = "1",

language = "English",

pages = "2303--2305",

booktitle = "18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014",

publisher = "Royal Society of Chemistry",

address = "United Kingdom",

note = "18th Intermational Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014, MicroTAS 2014 ; Conference date: 26-10-2014 Through 30-10-2014",

url = "http://www.microtasconferences.org/microtas2014/",

}

Visser, EWA , IJzendoorn, van, LJ & Prins, MWJ 2014, Tethered particle motion (TPM) characterizes binding types for lab-on-a-chip biosensing. in 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Royal Society of Chemistry, blz. 2303-2305, 18th Intermational Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014, San Antonio, Texas, Verenigde Staten van Amerika, 26/10/14.

Tethered particle motion (TPM) characterizes binding types for lab-on-a-chip biosensing. / Visser, E.W.A.; IJzendoorn, van, L.J.; Prins, M.W.J.
18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Royal Society of Chemistry, 2014. blz. 2303-2305.

Onderzoeksoutput: Hoofdstuk in Boek/Rapport/Congresprocedure › Conferentiebijdrage › Academic › peer review

TY - GEN

T1 - Tethered particle motion (TPM) characterizes binding types for lab-on-a-chip biosensing

AU - Visser, E.W.A.

AU - IJzendoorn, van, L.J.

AU - Prins, M.W.J.

N1 - Conference code: 18

PY - 2014/1/1

Y1 - 2014/1/1

N2 - We present a study on the application of tethered particle motion (TPM) for biosensing. Specifically, we investigate the dynamics of surface bound particles using TPM. In a model system, we demonstrate that particle binding to a sensor surface can be controlled via single tethers and via multiple tethers, and that the binding types can be quantified with TPM in an optical biosensing system.

AB - We present a study on the application of tethered particle motion (TPM) for biosensing. Specifically, we investigate the dynamics of surface bound particles using TPM. In a model system, we demonstrate that particle binding to a sensor surface can be controlled via single tethers and via multiple tethers, and that the binding types can be quantified with TPM in an optical biosensing system.

KW - Biosensing

KW - Bond discrimination

KW - Bond dynamics

KW - Particles

KW - Tethered particle motion

UR - http://www.scopus.com/inward/record.url?scp=84941662870&partnerID=8YFLogxK

M3 - Conference contribution

SP - 2303

EP - 2305

BT - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014

PB - Royal Society of Chemistry

T2 - 18th Intermational Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014

Y2 - 26 October 2014 through 30 October 2014

ER -

Tethered particle motion (TPM) characterizes binding types for lab-on-a-chip biosensing

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Congres

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