Supramolecular biomaterials

Matthew J. Webber, Eric A. Appel, E. W. Meijer, Robert Langer

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

841 Citaten (Scopus)
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Samenvatting

Polymers, ceramics and metals have historically dominated the application of materials in medicine. Yet rationally designed materials that exploit specific, directional, tunable and reversible non-covalent interactions offer unprecedented advantages: they enable modular and generalizable platforms with tunable mechanical, chemical and biological properties. Indeed, the reversible nature of supramolecular interactions gives rise to biomaterials that can sense and respond to physiological cues, or that mimic the structural and functional aspects of biological signalling. In this Review, we discuss the properties of several supramolecular biomaterials, as well as their applications in drug delivery, tissue engineering, regenerative medicine and immunology. We envision that supramolecular biomaterials will contribute to the development of new therapies that combine highly functional materials with unmatched patient- and application-specific tailoring of both material and biological properties.

Originele taal-2Engels
Pagina's (van-tot)13-26
Aantal pagina's14
TijdschriftNature Materials
Volume15
Nummer van het tijdschrift1
DOI's
StatusGepubliceerd - 18 dec 2015

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