Strong reduction of spectral heterogeneity in gold bipyramids for single-particle and single-molecule plasmon sensing

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

9 Citaten (Scopus)
8 Downloads (Pure)

Samenvatting

Single metal nanoparticles are attractive biomolecular sensors. Binding of analyte to a functional particle results in a plasmon shift that can be conveniently monitored in a far-field optical microscope. Heterogeneities in spectral properties of individual particles in an ensemble affect the reliability of a single-particle plasmon sensor, especially when plasmon shifts are monitored in real-time using a fixed irradiation wavelength. We compare the spectral heterogeneity of different plasmon sensor geometries (gold nanospheres, nanorods, and bipyramids) and correlate this to their size and aspect-ratio dispersion. We show that gold bipyramids exhibit a strongly reduced heterogeneity in aspect ratio and plasmon wavelength compared to commonly used gold nanorods. We show that this translates into a significantly improved homogeneity of the response to molecular binding without compromising single-molecule sensitivity.
Originele taal-2Engels
Artikelnummer024001
Aantal pagina's7
TijdschriftNanotechnology
Volume27
Nummer van het tijdschrift2
DOI's
StatusGepubliceerd - 15 jan 2016

Citeer dit