STAPLE performance assessed on crowdsourced sclera segmentations

Malte-Levin Jauer, Saksham Goel, Yash Sharma, Thomas M. Deserno, Marlies Gijs, Tos T. J. M. Berendschot, Christian J. F. Bertens, Rudy M. M. A. Nuijts

Onderzoeksoutput: Hoofdstuk in Boek/Rapport/CongresprocedureConferentiebijdrageAcademicpeer review

4 Citaten (Scopus)


The Simultaneous Truth and Performance Level Estimation (STAPLE) algorithm is frequently used in medical image segmentation without available ground truth (GT). In this paper, we investigate the number of inexperi- enced users required to establish a reliable STAPLE-based GT and the number of vertices the user's shall place for a point-based segmentation. We employ "WeLineation", a novel web-based system for crowdsourcing seg- mentations. Within the study, 2,060 masks have been delivered by 44 users on 75 different photographic images of the human eye, where users had to segment the sclera. For all masks, GT was estimated using STAPLE. Then, STAPLE is computed using fewer user contributions and results are compared to the GT. Requiring an error rate lower than 2%, same segmentation performance is obtained with 13 experienced and 22 rather inexperienced users. More than 10 vertices shall be placed on the delineation contour in order to reach an accuracy larger than 95%. In average, a vertex along the segmentation contour shall be placed every 81 pixels. The results indicate that knowledge about the users performance can reduce the number of segmentation masks per image, which are needed to estimate reliable GT. Therefore, gathering performance parameters of users during a crowdsourcing study and applying this information to the assignment process is recommended. In this way, benefits in the cost-effectiveness of a crowdsourcing segmentation study can be achieved.

Originele taal-2Engels
TitelMedical Imaging 2020: Imaging Informatics for Healthcare, Research, and Applications
RedacteurenPo-Hao Chen, Thomas M. Deserno
ISBN van elektronische versie9781510634039
StatusGepubliceerd - 2020

Publicatie series

NaamProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN van geprinte versie1605-7422


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