Samenvatting
Objective: Tissue mechanical properties are valuable markers for tissue characterization, aiding in the detection and staging of pathologies. Shear wave elastography (SWE) offers a quantitative assessment of tissue mechanical characteristics based on the SW propagation profile, which is derived from the SW particle motion. Improving the signal-to-noise ratio (SNR) of the SW particle motion would directly enhance the accuracy of the material property estimates such as elasticity or viscosity.
Methods: In this paper, we present a 3-D multi-resolution convolutional neural network (MRCNN) to perform improved estimation of the SW particle velocity V. Additionally, we propose a novel approach to generate training data from real acquisitions, providing high SNR ground truth target data, one-to-one paired to inputs that are corrupted with real-world noise and disturbances.
Discussion: By testing the network on in vitro data acquired from a commercial breast elastography phantom, we show that the MRCNN outperforms Loupas’ autocorrelation algorithm with an improved SNR of 4.47 dB for the V signals, a two-fold decrease in the standard deviation of the downstream elasticity estimates, and a two-fold increase in the contrast-to-noise ratio of the elasticity maps. The generalizability of the network was further demonstrated with a set of ex vivo porcine liver data.
Conclusion: The proposed MRCNN outperforms the standard autocorrelation method, in particular in low SNR regimes.
Methods: In this paper, we present a 3-D multi-resolution convolutional neural network (MRCNN) to perform improved estimation of the SW particle velocity V. Additionally, we propose a novel approach to generate training data from real acquisitions, providing high SNR ground truth target data, one-to-one paired to inputs that are corrupted with real-world noise and disturbances.
Discussion: By testing the network on in vitro data acquired from a commercial breast elastography phantom, we show that the MRCNN outperforms Loupas’ autocorrelation algorithm with an improved SNR of 4.47 dB for the V signals, a two-fold decrease in the standard deviation of the downstream elasticity estimates, and a two-fold increase in the contrast-to-noise ratio of the elasticity maps. The generalizability of the network was further demonstrated with a set of ex vivo porcine liver data.
Conclusion: The proposed MRCNN outperforms the standard autocorrelation method, in particular in low SNR regimes.
Originele taal-2 | Engels |
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Pagina's (van-tot) | 1518-1526 |
Aantal pagina's | 9 |
Tijdschrift | Ultrasound in Medicine and Biology |
Volume | 49 |
Nummer van het tijdschrift | 7 |
DOI's | |
Status | Gepubliceerd - 1 jul. 2023 |