RTX Adhesins are key bacterial surface megaproteins in the formation of biofilms

Shuaiqi Guo, Tyler D.R. Vance, Corey A. Stevens, Ilja K. Voets, Peter L. Davies (Corresponding author)

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

Uittreksel

A mistake was present in an earlier version of the review article ‘RTX Adhesins are Key Bacterial Surface Megaproteins in the Formation of Biofilms’ by Guo et al. The last two sentences of the section 'Cell-Surface Retention Region: A Calcium-Independent Plug Anchors the Adhesin in the T1SS OMP' were 'Intriguingly, although the β-sandwich plug is conserved in the non-RTX adhesin of P. aeruginosa (CdrA), it lacks the T(P)-A-A-G site for proteolysis. Instead, CdrA is retained by a "cysteine hook" that restricts its secretion through the outer-membrane pore [80,81].' This text should read 'Intriguingly, although a T-A-A-G site for proteolysis is present in the non-RTX adhesin of P. aeruginosa (CdrA), this protein is retained by a ‘cysteine hook’ that restricts its secretion through the outer-membrane pore via the Type Vb secretion system [80,81].' This has now been corrected.
TaalEngels
Pagina's453-467
TijdschriftTrends in Microbiology
Volume27
Nummer van het tijdschrift5
Vroegere onlinedatum28 feb 2019
DOI's
StatusGepubliceerd - 1 mei 2019

Vingerafdruk

Bacterial Adhesins
Biofilms
Proteolysis
Cysteine
Membranes
Calcium
Proteins

Citeer dit

Guo, Shuaiqi ; Vance, Tyler D.R. ; Stevens, Corey A. ; Voets, Ilja K. ; Davies, Peter L./ RTX Adhesins are key bacterial surface megaproteins in the formation of biofilms. In: Trends in Microbiology. 2019 ; Vol. 27, Nr. 5. blz. 453-467
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abstract = "A mistake was present in an earlier version of the review article ‘RTX Adhesins are Key Bacterial Surface Megaproteins in the Formation of Biofilms’ by Guo et al. The last two sentences of the section 'Cell-Surface Retention Region: A Calcium-Independent Plug Anchors the Adhesin in the T1SS OMP' were 'Intriguingly, although the β-sandwich plug is conserved in the non-RTX adhesin of P. aeruginosa (CdrA), it lacks the T(P)-A-A-G site for proteolysis. Instead, CdrA is retained by a {"}cysteine hook{"} that restricts its secretion through the outer-membrane pore [80,81].' This text should read 'Intriguingly, although a T-A-A-G site for proteolysis is present in the non-RTX adhesin of P. aeruginosa (CdrA), this protein is retained by a ‘cysteine hook’ that restricts its secretion through the outer-membrane pore via the Type Vb secretion system [80,81].' This has now been corrected.",
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RTX Adhesins are key bacterial surface megaproteins in the formation of biofilms. / Guo, Shuaiqi; Vance, Tyler D.R.; Stevens, Corey A.; Voets, Ilja K.; Davies, Peter L. (Corresponding author).

In: Trends in Microbiology, Vol. 27, Nr. 5, 01.05.2019, blz. 453-467.

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

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