Rhodium-catalysed hydroformylation of N-(2-propenyl)-ß-lactams as a key step in the synthesis of functionalised N-[4-(2-oxoazetidin-1-yl)-but-1-enyl]acetamides

S. Dekeukeleire; M.W.A. D'hooghe; C. Müller; D. Vogt; N. De Kimpe

doi:10.1039/c0nj00146e

Rhodium-catalysed hydroformylation of N-(2-propenyl)-ß-lactams as a key step in the synthesis of functionalised N-[4-(2-oxoazetidin-1-yl)-but-1-enyl]acetamides

S. Dekeukeleire, M.W.A. D'hooghe, C. Müller, D. Vogt, N. De Kimpe

Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review

17 Citaten (Scopus)

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Biologically relevant functionalised N-[4-(2-oxoazetidin-1-yl)-but-1-enyl]acetamides have been prepared in a two-step approach starting from N-(2-propenyl)--lactams, involving initial rhodium-catalysed hydroformylation followed by subjection of the obtained aldehydes to Staudinger reaction conditions after initial imination.

Originele taal-2	Engels
Pagina's (van-tot)	1079-1083
Aantal pagina's	4
Tijdschrift	New Journal of Chemistry
Volume	34
DOI's	https://doi.org/10.1039/c0nj00146e
Status	Gepubliceerd - 2010

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title = "Rhodium-catalysed hydroformylation of N-(2-propenyl)-{\ss}-lactams as a key step in the synthesis of functionalised N-[4-(2-oxoazetidin-1-yl)-but-1-enyl]acetamides",

abstract = "Biologically relevant functionalised N-[4-(2-oxoazetidin-1-yl)-but-1-enyl]acetamides have been prepared in a two-step approach starting from N-(2-propenyl)--lactams, involving initial rhodium-catalysed hydroformylation followed by subjection of the obtained aldehydes to Staudinger reaction conditions after initial imination.",

author = "S. Dekeukeleire and M.W.A. D'hooghe and C. M{\"u}ller and D. Vogt and {De Kimpe}, N.",

year = "2010",

doi = "10.1039/c0nj00146e",

language = "English",

volume = "34",

pages = "1079--1083",

journal = "New Journal of Chemistry",

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publisher = "Royal Society of Chemistry",

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Rhodium-catalysed hydroformylation of N-(2-propenyl)-ß-lactams as a key step in the synthesis of functionalised N-[4-(2-oxoazetidin-1-yl)-but-1-enyl]acetamides. / Dekeukeleire, S.; D'hooghe, M.W.A.; Müller, C. et al.
In: New Journal of Chemistry, Vol. 34, 2010, blz. 1079-1083.

Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review

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AU - Dekeukeleire, S.

AU - D'hooghe, M.W.A.

AU - Müller, C.

AU - Vogt, D.

AU - De Kimpe, N.

PY - 2010

Y1 - 2010

N2 - Biologically relevant functionalised N-[4-(2-oxoazetidin-1-yl)-but-1-enyl]acetamides have been prepared in a two-step approach starting from N-(2-propenyl)--lactams, involving initial rhodium-catalysed hydroformylation followed by subjection of the obtained aldehydes to Staudinger reaction conditions after initial imination.

AB - Biologically relevant functionalised N-[4-(2-oxoazetidin-1-yl)-but-1-enyl]acetamides have been prepared in a two-step approach starting from N-(2-propenyl)--lactams, involving initial rhodium-catalysed hydroformylation followed by subjection of the obtained aldehydes to Staudinger reaction conditions after initial imination.

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DO - 10.1039/c0nj00146e

M3 - Article

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VL - 34

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JO - New Journal of Chemistry

JF - New Journal of Chemistry

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Rhodium-catalysed hydroformylation of N-(2-propenyl)-ß-lactams as a key step in the synthesis of functionalised N-[4-(2-oxoazetidin-1-yl)-but-1-enyl]acetamides

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