Reducing distortions in echo-planar breast imaging at ultrahigh field with high-resolution off-resonance maps

Michael J. van Rijssel (Corresponding author), Frank Zijlstra, Peter R. Seevinck, Peter R. Luijten, Kenneth G.A. Gilhuijs, Dennis W.J. Klomp, Josien P.W. Pluim

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

Uittreksel

PURPOSE: DWI is a promising modality in breast MRI, but its clinical acceptance is slow. Analysis of DWI is hampered by geometric distortion artifacts, which are caused by off-resonant spins in combination with the low phase-encoding bandwidth of the EPI sequence used. Existing correction methods assume smooth off-resonance fields, which we show to be invalid in the human breast, where high discontinuities arise at tissue interfaces.

METHODS: We developed a distortion correction method that incorporates high-resolution off-resonance maps to better solve for severe distortions at tissue interfaces. The method was evaluated quantitatively both ex vivo in a porcine tissue phantom and in vivo in 5 healthy volunteers. The added value of high-resolution off-resonance maps was tested using a Wilcoxon signed rank test comparing the quantitative results obtained with a low-resolution off-resonance map with those obtained with a high-resolution map.

RESULTS: Distortion correction using low-resolution off-resonance maps corrected most of the distortions, as expected. Still, all quantitative comparison metrics showed increased conformity between the corrected EPI images and a high-bandwidth reference scan for both the ex vivo and in vivo experiments. All metrics showed a significant improvement when a high-resolution off-resonance map was used (P < 0.05), in particular at tissue boundaries.

CONCLUSION: The use of off-resonance maps of a resolution higher than EPI scans significantly improves upon existing distortion correction techniques, specifically by superior correction at glandular tissue boundaries.

TaalEngels
Pagina's425-435
Aantal pagina's11
TijdschriftMagnetic Resonance in Medicine
Volume82
Nummer van het tijdschrift1
Vroegere onlinedatum1 mrt 2019
DOI's
StatusGepubliceerd - jul 2019

Vingerafdruk

Echo-Planar Imaging
Breast
Nonparametric Statistics
Artifacts
Healthy Volunteers
Swine

Trefwoorden

    Citeer dit

    van Rijssel, M. J., Zijlstra, F., Seevinck, P. R., Luijten, P. R., Gilhuijs, K. G. A., Klomp, D. W. J., & Pluim, J. P. W. (2019). Reducing distortions in echo-planar breast imaging at ultrahigh field with high-resolution off-resonance maps. Magnetic Resonance in Medicine, 82(1), 425-435. DOI: 10.1002/mrm.27701
    van Rijssel, Michael J. ; Zijlstra, Frank ; Seevinck, Peter R. ; Luijten, Peter R. ; Gilhuijs, Kenneth G.A. ; Klomp, Dennis W.J. ; Pluim, Josien P.W./ Reducing distortions in echo-planar breast imaging at ultrahigh field with high-resolution off-resonance maps. In: Magnetic Resonance in Medicine. 2019 ; Vol. 82, Nr. 1. blz. 425-435
    @article{f76a261c566d40bd85959182e48aec22,
    title = "Reducing distortions in echo-planar breast imaging at ultrahigh field with high-resolution off-resonance maps",
    abstract = "PURPOSE: DWI is a promising modality in breast MRI, but its clinical acceptance is slow. Analysis of DWI is hampered by geometric distortion artifacts, which are caused by off-resonant spins in combination with the low phase-encoding bandwidth of the EPI sequence used. Existing correction methods assume smooth off-resonance fields, which we show to be invalid in the human breast, where high discontinuities arise at tissue interfaces.METHODS: We developed a distortion correction method that incorporates high-resolution off-resonance maps to better solve for severe distortions at tissue interfaces. The method was evaluated quantitatively both ex vivo in a porcine tissue phantom and in vivo in 5 healthy volunteers. The added value of high-resolution off-resonance maps was tested using a Wilcoxon signed rank test comparing the quantitative results obtained with a low-resolution off-resonance map with those obtained with a high-resolution map.RESULTS: Distortion correction using low-resolution off-resonance maps corrected most of the distortions, as expected. Still, all quantitative comparison metrics showed increased conformity between the corrected EPI images and a high-bandwidth reference scan for both the ex vivo and in vivo experiments. All metrics showed a significant improvement when a high-resolution off-resonance map was used (P < 0.05), in particular at tissue boundaries.CONCLUSION: The use of off-resonance maps of a resolution higher than EPI scans significantly improves upon existing distortion correction techniques, specifically by superior correction at glandular tissue boundaries.",
    keywords = "7T, B mapping, breast, diffusion-weighted imaging, distortion correction, echo-planar imaging, off-resonance",
    author = "{van Rijssel}, {Michael J.} and Frank Zijlstra and Seevinck, {Peter R.} and Luijten, {Peter R.} and Gilhuijs, {Kenneth G.A.} and Klomp, {Dennis W.J.} and Pluim, {Josien P.W.}",
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    year = "2019",
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    van Rijssel, MJ, Zijlstra, F, Seevinck, PR, Luijten, PR, Gilhuijs, KGA, Klomp, DWJ & Pluim, JPW 2019, 'Reducing distortions in echo-planar breast imaging at ultrahigh field with high-resolution off-resonance maps' Magnetic Resonance in Medicine, vol. 82, nr. 1, blz. 425-435. DOI: 10.1002/mrm.27701

    Reducing distortions in echo-planar breast imaging at ultrahigh field with high-resolution off-resonance maps. / van Rijssel, Michael J. (Corresponding author); Zijlstra, Frank; Seevinck, Peter R.; Luijten, Peter R.; Gilhuijs, Kenneth G.A.; Klomp, Dennis W.J.; Pluim, Josien P.W.

    In: Magnetic Resonance in Medicine, Vol. 82, Nr. 1, 07.2019, blz. 425-435.

    Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

    TY - JOUR

    T1 - Reducing distortions in echo-planar breast imaging at ultrahigh field with high-resolution off-resonance maps

    AU - van Rijssel,Michael J.

    AU - Zijlstra,Frank

    AU - Seevinck,Peter R.

    AU - Luijten,Peter R.

    AU - Gilhuijs,Kenneth G.A.

    AU - Klomp,Dennis W.J.

    AU - Pluim,Josien P.W.

    N1 - © 2019 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine.

    PY - 2019/7

    Y1 - 2019/7

    N2 - PURPOSE: DWI is a promising modality in breast MRI, but its clinical acceptance is slow. Analysis of DWI is hampered by geometric distortion artifacts, which are caused by off-resonant spins in combination with the low phase-encoding bandwidth of the EPI sequence used. Existing correction methods assume smooth off-resonance fields, which we show to be invalid in the human breast, where high discontinuities arise at tissue interfaces.METHODS: We developed a distortion correction method that incorporates high-resolution off-resonance maps to better solve for severe distortions at tissue interfaces. The method was evaluated quantitatively both ex vivo in a porcine tissue phantom and in vivo in 5 healthy volunteers. The added value of high-resolution off-resonance maps was tested using a Wilcoxon signed rank test comparing the quantitative results obtained with a low-resolution off-resonance map with those obtained with a high-resolution map.RESULTS: Distortion correction using low-resolution off-resonance maps corrected most of the distortions, as expected. Still, all quantitative comparison metrics showed increased conformity between the corrected EPI images and a high-bandwidth reference scan for both the ex vivo and in vivo experiments. All metrics showed a significant improvement when a high-resolution off-resonance map was used (P < 0.05), in particular at tissue boundaries.CONCLUSION: The use of off-resonance maps of a resolution higher than EPI scans significantly improves upon existing distortion correction techniques, specifically by superior correction at glandular tissue boundaries.

    AB - PURPOSE: DWI is a promising modality in breast MRI, but its clinical acceptance is slow. Analysis of DWI is hampered by geometric distortion artifacts, which are caused by off-resonant spins in combination with the low phase-encoding bandwidth of the EPI sequence used. Existing correction methods assume smooth off-resonance fields, which we show to be invalid in the human breast, where high discontinuities arise at tissue interfaces.METHODS: We developed a distortion correction method that incorporates high-resolution off-resonance maps to better solve for severe distortions at tissue interfaces. The method was evaluated quantitatively both ex vivo in a porcine tissue phantom and in vivo in 5 healthy volunteers. The added value of high-resolution off-resonance maps was tested using a Wilcoxon signed rank test comparing the quantitative results obtained with a low-resolution off-resonance map with those obtained with a high-resolution map.RESULTS: Distortion correction using low-resolution off-resonance maps corrected most of the distortions, as expected. Still, all quantitative comparison metrics showed increased conformity between the corrected EPI images and a high-bandwidth reference scan for both the ex vivo and in vivo experiments. All metrics showed a significant improvement when a high-resolution off-resonance map was used (P < 0.05), in particular at tissue boundaries.CONCLUSION: The use of off-resonance maps of a resolution higher than EPI scans significantly improves upon existing distortion correction techniques, specifically by superior correction at glandular tissue boundaries.

    KW - 7T

    KW - B mapping

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    KW - diffusion-weighted imaging

    KW - distortion correction

    KW - echo-planar imaging

    KW - off-resonance

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    van Rijssel MJ, Zijlstra F, Seevinck PR, Luijten PR, Gilhuijs KGA, Klomp DWJ et al. Reducing distortions in echo-planar breast imaging at ultrahigh field with high-resolution off-resonance maps. Magnetic Resonance in Medicine. 2019 jul;82(1):425-435. Beschikbaar vanaf, DOI: 10.1002/mrm.27701