Peroxiredoxin proteins as building blocks for nanotechnology

Frankie Conroy, Amy Yewdall

Onderzoeksoutput: Hoofdstuk in Boek/Rapport/CongresprocedureHoofdstukAcademicpeer review


Peroxiredoxins are ubiquitous antioxidant proteins that exhibit a striking variety of quaternary structures, making them appealing building blocks with which nanoscale architectures are created for applications in nanotechnology. The solution environment of the protein, as well as protein sequence, influences the presentation of a particular structure, thereby enabling mesoscopic manipulations that affect arrangments at the nanoscale. This chapter will equip us with the knowledge necessary to not only produce and manipulate peroxiredoxin proteins into desired structures but also to characterize the different structures using dynamic light scattering, analytical centrifugation, and negative stain transmission electron microscopy, thereby setting the stage for us to use these proteins for applications in nanotechnology.

Originele taal-2Engels
TitelProtein Nanotechnology
RedacteurenJ. Gerard, L. Domigan
Plaats van productieHumana
Aantal pagina's16
ISBN van elektronische versie978-1-4939-9869-2
ISBN van geprinte versie978-1-4939-9868-5
StatusGepubliceerd - 2020

Publicatie series

NaamMethods in Molecular Biology
ISSN van geprinte versie1064-3745
ISSN van elektronische versie1940-6029


Citeer dit

Conroy, F., & Yewdall, A. (2020). Peroxiredoxin proteins as building blocks for nanotechnology. In J. Gerard, & L. Domigan (editors), Protein Nanotechnology (blz. 39-54). (Methods in Molecular Biology; Vol. 2073). Humana: Springer.