Perfluoroarene induces a pentapeptidic hydrotrope into a pH-tolerant hydrogel allowing naked eye sensing of Ca2+ ions

Bappa Maiti, Subham Bhattacharjee, Santanu Bhattacharya (Corresponding author)

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

1 Citaat (Scopus)

Uittreksel

Self-assembly of a novel thermoresponsive, pyrene-appended oligopeptide sequence VPGKP (PyP) leads to the formation of spherical aggregates in water. The sizes of the globular aggregates of the peptide, PyP, strongly depend on the temperature of its suspension in water and decrease with the decrease in temperature showing a lower critical solution temperature (LCST) phenomenon. Furthermore, a pyrene-octafluoronaphthalene (OFN) 'pair' has been used as a supramolecular synthon to induce hydrogelation of PyP in the presence of an equimolar amount of OFN via complementary quadrupole-quadrupole interactions. The gel shows excellent pH tolerance and thixotropic behavior. Detailed studies suggest the existence of lamellar packing of the gelators in a right-handed helical fashion which yields globular aggregates. The globular aggregates are sticky in nature and form a gel via inter-globular interactions. Addition of Ca2+ ions reinforces the mechanical strength and also reduces the critical gelator concentration of the native gel through coordination with the free -COO- group of the gelator. Therefore, the present hydrogel system could further be used as a naked eye sensor of Ca2+ ions.

TaalEngels
Pagina's2223-2230
Aantal pagina's8
TijdschriftNanoscale
Volume11
Nummer van het tijdschrift5
DOI's
StatusGepubliceerd - 7 feb 2019

Vingerafdruk

Hydrogel
Hydrogels
Ions
Gels
Pyrene
Oligopeptides
Water
Temperature
Self assembly
Peptides
Strength of materials
Suspensions
Sensors
octafluoronaphthalene
pyrene

Citeer dit

Maiti, Bappa ; Bhattacharjee, Subham ; Bhattacharya, Santanu. / Perfluoroarene induces a pentapeptidic hydrotrope into a pH-tolerant hydrogel allowing naked eye sensing of Ca2+ ions. In: Nanoscale. 2019 ; Vol. 11, Nr. 5. blz. 2223-2230
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abstract = "Self-assembly of a novel thermoresponsive, pyrene-appended oligopeptide sequence VPGKP (PyP) leads to the formation of spherical aggregates in water. The sizes of the globular aggregates of the peptide, PyP, strongly depend on the temperature of its suspension in water and decrease with the decrease in temperature showing a lower critical solution temperature (LCST) phenomenon. Furthermore, a pyrene-octafluoronaphthalene (OFN) 'pair' has been used as a supramolecular synthon to induce hydrogelation of PyP in the presence of an equimolar amount of OFN via complementary quadrupole-quadrupole interactions. The gel shows excellent pH tolerance and thixotropic behavior. Detailed studies suggest the existence of lamellar packing of the gelators in a right-handed helical fashion which yields globular aggregates. The globular aggregates are sticky in nature and form a gel via inter-globular interactions. Addition of Ca2+ ions reinforces the mechanical strength and also reduces the critical gelator concentration of the native gel through coordination with the free -COO- group of the gelator. Therefore, the present hydrogel system could further be used as a naked eye sensor of Ca2+ ions.",
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Perfluoroarene induces a pentapeptidic hydrotrope into a pH-tolerant hydrogel allowing naked eye sensing of Ca2+ ions. / Maiti, Bappa; Bhattacharjee, Subham; Bhattacharya, Santanu (Corresponding author).

In: Nanoscale, Vol. 11, Nr. 5, 07.02.2019, blz. 2223-2230.

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

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Maiti B, Bhattacharjee S, Bhattacharya S. Perfluoroarene induces a pentapeptidic hydrotrope into a pH-tolerant hydrogel allowing naked eye sensing of Ca2+ ions. Nanoscale. 2019 feb 7;11(5):2223-2230. Beschikbaar vanaf, DOI: 10.1039/c8nr08126c