Optical and acoustic characterization of freeze-thawed polyvinyl alcohol gels

Onderzoeksoutput: Hoofdstuk in Boek/Rapport/CongresprocedureConferentiebijdrageAcademicpeer review

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Uittreksel

Preclinical validation of non-invasive photoacoustic imaging of carotid artery atherosclerosis requires vessel phantoms that imitate optical, acoustic and mechanical properties of vascular tissue. Polyvinyl alcohol (PVA) phantoms that are widely used as ultrasound phantoms due to their elastic properties are also promising for photoacoustics. This study contributes to the field by quantifying the optical and acoustic properties of PVA gel, and aims at the characterization of realistic phantoms for future studies. In this study, we investigated the relation between acoustic scatterers and optical absorbers to quantify optical and acoustic properties of the PVA phantoms. Four different concentrations of orgasol acoustic scatterers, and varying concentration of Indian ink and molecular dye absorbers were added to a 15 wt% PVA solution. Samples were subjected to 1 to 5 freeze-thaw cycles and were examined after each cycle to quantify the effect on the optical and the acoustic properties. Optical attenuation was measured between 400 nm and 990 nm using a plate reader. Additionally, pulse-echo plane wave ultrasound was used for acoustic characterization. Changing the concentration of orgasol between 0.5 wt% and 4 wt% increased the mean optical attenuation of PVA by 35% after the first freeze thaw cycle. Likewise, each freeze-thaw cycle increased the optical attenuation due to scattering of light by the microstructure of PVA. The absorbance of pure PVA increased 40% between the first and second cycle and 3% between the fourth and fifth cycle. While the orgasol concentration and the freeze-thaw cycles altered the acoustic speed and attenuation, the ink and the dye inclusions did not significantly affect the acoustic properties of PVA.

Originele taal-2Engels
TitelIEEE International Ultrasonics Symposium, IUS
UitgeverijIEEE Computer Society
Pagina's2410-2413
Aantal pagina's4
ISBN van geprinte versie9781479970490
DOI's
StatusGepubliceerd - 20 okt 2014
Evenement2014 IEEE International Ultrasonics Symposium (IUS 2014) - Hilton Hotel, Chicago, Verenigde Staten van Amerika
Duur: 3 sep 20146 sep 2014
http://ewh.ieee.org/conf/ius_2014/

Congres

Congres2014 IEEE International Ultrasonics Symposium (IUS 2014)
Verkorte titelIUS 2014
LandVerenigde Staten van Amerika
StadChicago
Periode3/09/146/09/14
AnderInternational Ultrasonics Symposium
Internet adres

Vingerafdruk

polyvinyl alcohol
acoustic properties
gels
acoustics
cycles
attenuation
inks
optical properties
absorbers
dyes
scattering
arteriosclerosis
readers
arteries
vessels
echoes
plane waves
elastic properties
mechanical properties
inclusions

Citeer dit

Arabul, Ü., Rutten, M., Van De Vosse, F., & Lopata, R. (2014). Optical and acoustic characterization of freeze-thawed polyvinyl alcohol gels. In IEEE International Ultrasonics Symposium, IUS (blz. 2410-2413). [6932093] IEEE Computer Society. https://doi.org/10.1109/ULTSYM.2014.0601
Arabul, Ü. ; Rutten, M. ; Van De Vosse, F. ; Lopata, R. / Optical and acoustic characterization of freeze-thawed polyvinyl alcohol gels. IEEE International Ultrasonics Symposium, IUS. IEEE Computer Society, 2014. blz. 2410-2413
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title = "Optical and acoustic characterization of freeze-thawed polyvinyl alcohol gels",
abstract = "Preclinical validation of non-invasive photoacoustic imaging of carotid artery atherosclerosis requires vessel phantoms that imitate optical, acoustic and mechanical properties of vascular tissue. Polyvinyl alcohol (PVA) phantoms that are widely used as ultrasound phantoms due to their elastic properties are also promising for photoacoustics. This study contributes to the field by quantifying the optical and acoustic properties of PVA gel, and aims at the characterization of realistic phantoms for future studies. In this study, we investigated the relation between acoustic scatterers and optical absorbers to quantify optical and acoustic properties of the PVA phantoms. Four different concentrations of orgasol acoustic scatterers, and varying concentration of Indian ink and molecular dye absorbers were added to a 15 wt{\%} PVA solution. Samples were subjected to 1 to 5 freeze-thaw cycles and were examined after each cycle to quantify the effect on the optical and the acoustic properties. Optical attenuation was measured between 400 nm and 990 nm using a plate reader. Additionally, pulse-echo plane wave ultrasound was used for acoustic characterization. Changing the concentration of orgasol between 0.5 wt{\%} and 4 wt{\%} increased the mean optical attenuation of PVA by 35{\%} after the first freeze thaw cycle. Likewise, each freeze-thaw cycle increased the optical attenuation due to scattering of light by the microstructure of PVA. The absorbance of pure PVA increased 40{\%} between the first and second cycle and 3{\%} between the fourth and fifth cycle. While the orgasol concentration and the freeze-thaw cycles altered the acoustic speed and attenuation, the ink and the dye inclusions did not significantly affect the acoustic properties of PVA.",
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Arabul, Ü, Rutten, M, Van De Vosse, F & Lopata, R 2014, Optical and acoustic characterization of freeze-thawed polyvinyl alcohol gels. in IEEE International Ultrasonics Symposium, IUS., 6932093, IEEE Computer Society, blz. 2410-2413, 2014 IEEE International Ultrasonics Symposium (IUS 2014), Chicago, Verenigde Staten van Amerika, 3/09/14. https://doi.org/10.1109/ULTSYM.2014.0601

Optical and acoustic characterization of freeze-thawed polyvinyl alcohol gels. / Arabul, Ü.; Rutten, M.; Van De Vosse, F.; Lopata, R.

IEEE International Ultrasonics Symposium, IUS. IEEE Computer Society, 2014. blz. 2410-2413 6932093.

Onderzoeksoutput: Hoofdstuk in Boek/Rapport/CongresprocedureConferentiebijdrageAcademicpeer review

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AU - Rutten, M.

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N2 - Preclinical validation of non-invasive photoacoustic imaging of carotid artery atherosclerosis requires vessel phantoms that imitate optical, acoustic and mechanical properties of vascular tissue. Polyvinyl alcohol (PVA) phantoms that are widely used as ultrasound phantoms due to their elastic properties are also promising for photoacoustics. This study contributes to the field by quantifying the optical and acoustic properties of PVA gel, and aims at the characterization of realistic phantoms for future studies. In this study, we investigated the relation between acoustic scatterers and optical absorbers to quantify optical and acoustic properties of the PVA phantoms. Four different concentrations of orgasol acoustic scatterers, and varying concentration of Indian ink and molecular dye absorbers were added to a 15 wt% PVA solution. Samples were subjected to 1 to 5 freeze-thaw cycles and were examined after each cycle to quantify the effect on the optical and the acoustic properties. Optical attenuation was measured between 400 nm and 990 nm using a plate reader. Additionally, pulse-echo plane wave ultrasound was used for acoustic characterization. Changing the concentration of orgasol between 0.5 wt% and 4 wt% increased the mean optical attenuation of PVA by 35% after the first freeze thaw cycle. Likewise, each freeze-thaw cycle increased the optical attenuation due to scattering of light by the microstructure of PVA. The absorbance of pure PVA increased 40% between the first and second cycle and 3% between the fourth and fifth cycle. While the orgasol concentration and the freeze-thaw cycles altered the acoustic speed and attenuation, the ink and the dye inclusions did not significantly affect the acoustic properties of PVA.

AB - Preclinical validation of non-invasive photoacoustic imaging of carotid artery atherosclerosis requires vessel phantoms that imitate optical, acoustic and mechanical properties of vascular tissue. Polyvinyl alcohol (PVA) phantoms that are widely used as ultrasound phantoms due to their elastic properties are also promising for photoacoustics. This study contributes to the field by quantifying the optical and acoustic properties of PVA gel, and aims at the characterization of realistic phantoms for future studies. In this study, we investigated the relation between acoustic scatterers and optical absorbers to quantify optical and acoustic properties of the PVA phantoms. Four different concentrations of orgasol acoustic scatterers, and varying concentration of Indian ink and molecular dye absorbers were added to a 15 wt% PVA solution. Samples were subjected to 1 to 5 freeze-thaw cycles and were examined after each cycle to quantify the effect on the optical and the acoustic properties. Optical attenuation was measured between 400 nm and 990 nm using a plate reader. Additionally, pulse-echo plane wave ultrasound was used for acoustic characterization. Changing the concentration of orgasol between 0.5 wt% and 4 wt% increased the mean optical attenuation of PVA by 35% after the first freeze thaw cycle. Likewise, each freeze-thaw cycle increased the optical attenuation due to scattering of light by the microstructure of PVA. The absorbance of pure PVA increased 40% between the first and second cycle and 3% between the fourth and fifth cycle. While the orgasol concentration and the freeze-thaw cycles altered the acoustic speed and attenuation, the ink and the dye inclusions did not significantly affect the acoustic properties of PVA.

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BT - IEEE International Ultrasonics Symposium, IUS

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Arabul Ü, Rutten M, Van De Vosse F, Lopata R. Optical and acoustic characterization of freeze-thawed polyvinyl alcohol gels. In IEEE International Ultrasonics Symposium, IUS. IEEE Computer Society. 2014. blz. 2410-2413. 6932093 https://doi.org/10.1109/ULTSYM.2014.0601