On complex coacervate core micelles: Structure-function perspectives

Jose Rodrigo Magana; Christian C.M. Sproncken; Ilja K. Voets

doi:10.3390/POLYM12091953

On complex coacervate core micelles: Structure-function perspectives

Jose Rodrigo Magana
, Christian C.M. Sproncken
, Ilja K. Voets (Corresponding author)

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Onderzoeksoutput: Bijdrage aan tijdschrift › Artikel recenseren › peer review

64 Citaten (Scopus)

Samenvatting

The co-assembly of ionic-neutral block copolymers with oppositely charged species produces nanometric colloidal complexes, known, among other names, as complex coacervates core micelles (C3Ms). C3Ms are of widespread interest in nanomedicine for controlled delivery and release, whilst research activity into other application areas, such as gelation, catalysis, nanoparticle synthesis, and sensing, is increasing. In this review, we discuss recent studies on the functional roles that C3Ms can fulfil in these and other fields, focusing on emerging structure-function relations and remaining knowledge gaps.

Originele taal-2	Engels
Artikelnummer	1953
Aantal pagina's	37
Tijdschrift	Polymers
Volume	12
Nummer van het tijdschrift	9
DOI's	https://doi.org/10.3390/POLYM12091953
Status	Gepubliceerd - 28 aug. 2020

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Funding: The Netherlands Organization for Scientific Research (NWO TA Grant No. 731.015.205 and NWO LIFT Grant 731.017.407) is gratefully acknowledged for financial support.

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title = "On complex coacervate core micelles: Structure-function perspectives",

abstract = "The co-assembly of ionic-neutral block copolymers with oppositely charged species produces nanometric colloidal complexes, known, among other names, as complex coacervates core micelles (C3Ms). C3Ms are of widespread interest in nanomedicine for controlled delivery and release, whilst research activity into other application areas, such as gelation, catalysis, nanoparticle synthesis, and sensing, is increasing. In this review, we discuss recent studies on the functional roles that C3Ms can fulfil in these and other fields, focusing on emerging structure-function relations and remaining knowledge gaps.",

keywords = "Co-assembly, Complex coacervate core micelle, Interpolyelectrolyte complex, Polyelectrolytes, Polyion complex, Polyplex, Protein-polymer complex, Structure-function relations",

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T2 - Structure-function perspectives

AU - Magana, Jose Rodrigo

AU - Sproncken, Christian C.M.

AU - Voets, Ilja K.

PY - 2020/8/28

Y1 - 2020/8/28

N2 - The co-assembly of ionic-neutral block copolymers with oppositely charged species produces nanometric colloidal complexes, known, among other names, as complex coacervates core micelles (C3Ms). C3Ms are of widespread interest in nanomedicine for controlled delivery and release, whilst research activity into other application areas, such as gelation, catalysis, nanoparticle synthesis, and sensing, is increasing. In this review, we discuss recent studies on the functional roles that C3Ms can fulfil in these and other fields, focusing on emerging structure-function relations and remaining knowledge gaps.

AB - The co-assembly of ionic-neutral block copolymers with oppositely charged species produces nanometric colloidal complexes, known, among other names, as complex coacervates core micelles (C3Ms). C3Ms are of widespread interest in nanomedicine for controlled delivery and release, whilst research activity into other application areas, such as gelation, catalysis, nanoparticle synthesis, and sensing, is increasing. In this review, we discuss recent studies on the functional roles that C3Ms can fulfil in these and other fields, focusing on emerging structure-function relations and remaining knowledge gaps.

KW - Co-assembly

KW - Complex coacervate core micelle

KW - Interpolyelectrolyte complex

KW - Polyelectrolytes

KW - Polyion complex

KW - Polyplex

KW - Protein-polymer complex

KW - Structure-function relations

UR - https://www.scopus.com/pages/publications/85091340089

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DO - 10.3390/POLYM12091953

M3 - Review article

C2 - 32872312

AN - SCOPUS:85091340089

SN - 2073-4360

VL - 12

JO - Polymers

JF - Polymers

IS - 9

M1 - 1953

ER -

On complex coacervate core micelles: Structure-function perspectives

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