Novel lipidomimetic compounds and uses thereof

Holger Gruell; Sander Langereis; Johan Lub

Novel lipidomimetic compounds and uses thereof

Holger Gruell (Uitvinder), Sander Langereis (Uitvinder), Johan Lub (Uitvinder)

Onderzoeksoutput: Octrooi › Octrooi-publicatie

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Disclosed are lipidomimetic compounds of formula I (I) wherein: G represents a group satisfying formula II: HO-CH2-{CH(OH)-CH2-0}m-CH2-{C(=0)-0-CH2}q- formula II each n independently is an integer from 1-30; m is an integer from 1-10; q is 0 or 1. These compounds can be added to the lipid bilayer of thermosensitive liposomes, for the purpose of aiding in the prevention of leakage of the liposomes' contents at 37°C, and retarding clearance from circulation.

Originele taal-2	Engels
Octrooinummer	WO2012172457
IPC	C07C 69/ 708 A I
Prioriteitsdatum	16/06/11
Status	Gepubliceerd - 20 dec. 2012

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title = "Novel lipidomimetic compounds and uses thereof",

abstract = "Disclosed are lipidomimetic compounds of formula I (I) wherein: G represents a group satisfying formula II: HO-CH2-{CH(OH)-CH2-0}m-CH2-{C(=0)-0-CH2}q- formula II each n independently is an integer from 1-30; m is an integer from 1-10; q is 0 or 1. These compounds can be added to the lipid bilayer of thermosensitive liposomes, for the purpose of aiding in the prevention of leakage of the liposomes' contents at 37°C, and retarding clearance from circulation.",

author = "Holger Gruell and Sander Langereis and Johan Lub",

year = "2012",

month = dec,

day = "20",

language = "English",

type = "Patent",

note = "WO2012172457; C07C 69/ 708 A I",

}

TY - PAT

T1 - Novel lipidomimetic compounds and uses thereof

AU - Gruell, Holger

AU - Langereis, Sander

AU - Lub, Johan

PY - 2012/12/20

Y1 - 2012/12/20

N2 - Disclosed are lipidomimetic compounds of formula I (I) wherein: G represents a group satisfying formula II: HO-CH2-{CH(OH)-CH2-0}m-CH2-{C(=0)-0-CH2}q- formula II each n independently is an integer from 1-30; m is an integer from 1-10; q is 0 or 1. These compounds can be added to the lipid bilayer of thermosensitive liposomes, for the purpose of aiding in the prevention of leakage of the liposomes' contents at 37°C, and retarding clearance from circulation.

AB - Disclosed are lipidomimetic compounds of formula I (I) wherein: G represents a group satisfying formula II: HO-CH2-{CH(OH)-CH2-0}m-CH2-{C(=0)-0-CH2}q- formula II each n independently is an integer from 1-30; m is an integer from 1-10; q is 0 or 1. These compounds can be added to the lipid bilayer of thermosensitive liposomes, for the purpose of aiding in the prevention of leakage of the liposomes' contents at 37°C, and retarding clearance from circulation.

M3 - Patent publication

M1 - WO2012172457

ER -

Novel lipidomimetic compounds and uses thereof

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