Novel lipidomimetic compounds and uses thereof

Holger Gruell (Uitvinder), Sander Langereis (Uitvinder), Johan Lub (Uitvinder)

    Onderzoeksoutput: OctrooiOctrooi-publicatie

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    Samenvatting

    Disclosed are lipidomimetic compounds of formula I (I) wherein: G represents a group satisfying formula II: HO-CH2-{CH(OH)-CH2-0}m-CH2-{C(=0)-0-CH2})q- formula II each n independently is an integer from 1-30; m is an integer from 1-10; q is 0 or 1. These compounds can be added to the lipid bilayer of thermosensitive liposomes, for the purpose of aiding in the prevention of leakage of the liposomes' contents at 37 DEG C., and retarding clearance from circulation.

    Originele taal-2Engels
    OctrooinummerUS2014127135
    IPCA61K 49/ 18 A I
    Prioriteitsdatum6/06/12
    StatusGepubliceerd - 8 mei 2014

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