Novel lipidomimetic compounds and uses thereof

Holger Gruell; Sander Langereis; Johan Lub

Novel lipidomimetic compounds and uses thereof

Holger Gruell (Uitvinder), Sander Langereis (Uitvinder), Johan Lub (Uitvinder)

Onderzoeksoutput: Octrooi › Octrooi-publicatie

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Disclosed are lipidomimetic compounds of formula I (I) wherein: G represents a group satisfying formula II: HO-CH2-{CH(OH)-CH2-0}m-CH2-{C(=0)-0-CH2})q- formula II each n independently is an integer from 1-30; m is an integer from 1-10; q is 0 or 1. These compounds can be added to the lipid bilayer of thermosensitive liposomes, for the purpose of aiding in the prevention of leakage of the liposomes' contents at 37 DEG C., and retarding clearance from circulation.

Originele taal-2	Engels
Octrooinummer	US2014127135
IPC	A61K 49/ 18 A I
Prioriteitsdatum	6/06/12
Status	Gepubliceerd - 8 mei 2014

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@misc{9765afb49f854f56b2b1f7be0d27321b,

title = "Novel lipidomimetic compounds and uses thereof",

abstract = "Disclosed are lipidomimetic compounds of formula I (I) wherein: G represents a group satisfying formula II: HO-CH2-{CH(OH)-CH2-0}m-CH2-{C(=0)-0-CH2})q- formula II each n independently is an integer from 1-30; m is an integer from 1-10; q is 0 or 1. These compounds can be added to the lipid bilayer of thermosensitive liposomes, for the purpose of aiding in the prevention of leakage of the liposomes' contents at 37 DEG C., and retarding clearance from circulation.",

author = "Holger Gruell and Sander Langereis and Johan Lub",

year = "2014",

month = may,

day = "8",

language = "English",

type = "Patent",

note = "US2014127135; A61K 49/ 18 A I",

}

TY - PAT

T1 - Novel lipidomimetic compounds and uses thereof

AU - Gruell, Holger

AU - Langereis, Sander

AU - Lub, Johan

PY - 2014/5/8

Y1 - 2014/5/8

N2 - Disclosed are lipidomimetic compounds of formula I (I) wherein: G represents a group satisfying formula II: HO-CH2-{CH(OH)-CH2-0}m-CH2-{C(=0)-0-CH2})q- formula II each n independently is an integer from 1-30; m is an integer from 1-10; q is 0 or 1. These compounds can be added to the lipid bilayer of thermosensitive liposomes, for the purpose of aiding in the prevention of leakage of the liposomes' contents at 37 DEG C., and retarding clearance from circulation.

AB - Disclosed are lipidomimetic compounds of formula I (I) wherein: G represents a group satisfying formula II: HO-CH2-{CH(OH)-CH2-0}m-CH2-{C(=0)-0-CH2})q- formula II each n independently is an integer from 1-30; m is an integer from 1-10; q is 0 or 1. These compounds can be added to the lipid bilayer of thermosensitive liposomes, for the purpose of aiding in the prevention of leakage of the liposomes' contents at 37 DEG C., and retarding clearance from circulation.

M3 - Patent publication

M1 - US2014127135

ER -

Novel lipidomimetic compounds and uses thereof

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