Non-linear viscoelastic behavior of abdominal aortic aneurysm thrombus

E.A. Dam, van, S.D. Dams, G.W.M. Peters, M.C.M. Rutten, G.W.H. Schurink, J. Buth, F.N. Vosse, van de

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Samenvatting

The objective of this work was to determine the linear and non-linear viscoelastic behavior of abdominal aortic aneurysm thrombus and to study the changes in mechanical properties throughout the thickness of the thrombus. Samples are gathered from thrombi of 7 patients. Linear viscoelastic data from oscillatory shear experiments show that the change of properties throughout the thrombus is different for each thrombus. Furthermore the variations found within one thrombusare of the same order of magnitude as the variation between patients. To study the non-linear regime, stress relaxation experiments are performed. To describe the phenomena observed experimentally,a non-linear multi mode model is presented. The parameters for this model are obtained by fitting this model successfully to the experiments. The model can not only describe the average stress response for all thrombus samples but also the highest and lowest stress responses. To determine the influence on the wall stress of the behavior observed the model proposed needs to be implemented in the finite element wall stress analysis.
Originele taal-2Engels
Pagina's (van-tot)127-137
TijdschriftBiomechanics and Modeling in Mechanobiology
Volume7
Nummer van het tijdschrift2
DOI's
StatusGepubliceerd - 2008

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