Morphology control of liposome - RAFT oligomer precursors to complex polymer nanostructures

Mohammad Amin Moradi (Corresponding author), Sam Tempelaar, Alexander M. Van Herk, Johan P.A. Heuts

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

2 Citaten (Scopus)
61 Downloads (Pure)

Samenvatting

Different types of butyl acrylate (BA)-co-acrylic acid (AA) oligomers were synthesized via reversible addition-fragmentation chain transfer (RAFT) polymerization and mixed with extruded 200 nm dimethyldioctadecylammonium bromide vesicles. The resulting precursor structures form the basis for subsequent vesicle-templated polymerizations. Systematic variations in temperature, pH, oligomer length, and oligomer composition and their effects on precursor morphology were studied. Surprisingly, different morphologies were obtained, including capsules, protruded capsules, solid spheres, and multicompartment structures. For example, capsules and multicompartment structures were found to result from higher AA contents, and protruded capsules and solid particles resulted from lower AA contents. Subsequent chain extension of the RAFT oligomers resulted in polymer nanostructures resembling the precursor morphologies.

Originele taal-2Engels
Artikelnummer24
Pagina's (van-tot)9476-9483
Aantal pagina's8
TijdschriftMacromolecules
Volume52
Nummer van het tijdschrift24
DOI's
StatusGepubliceerd - 24 dec 2019

Vingerafdruk

Duik in de onderzoeksthema's van 'Morphology control of liposome - RAFT oligomer precursors to complex polymer nanostructures'. Samen vormen ze een unieke vingerafdruk.

Citeer dit