Modular supramolecular ureidopyrimidinone polymer carriers for intracellular delivery

Maarten H. Bakker; Roxanne E. Kieltyka; Lorenzo Albertazzi; Patricia Y.W. Dankers

doi:10.1039/C6RA22490C

Modular supramolecular ureidopyrimidinone polymer carriers for intracellular delivery

Maarten H. Bakker
, Roxanne E. Kieltyka
, Lorenzo Albertazzi
, Patricia Y.W. Dankers

Institute for Complex Molecular Systems

Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review

27 Citaten (Scopus)

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Ureidopyrimidinone-based polymers in solution provide a new platform for intracellular drug delivery. Here we show the synthesis of functional supramolecular polymers by mixing of monomers with various functionalities. Introduction of cationic monomers made them suitable for cellular uptake and siRNA delivery.

Originele taal-2	Engels
Pagina's (van-tot)	110600-110603
Aantal pagina's	4
Tijdschrift	RSC Advances
Volume	6
Nummer van het tijdschrift	112
DOI's	https://doi.org/10.1039/C6RA22490C
Status	Gepubliceerd - 1 jan. 2016

Financiering

We thank the Ministry of Education, Culture and Science (Gravity program 024.001.035), the European Research Council (FP7/2007-2013) ERC Grant Agreement 308045, and the Netherlands Organization for Scientific Research (NWO-VENI Grant: 722.014.010) for funding.

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abstract = "Ureidopyrimidinone-based polymers in solution provide a new platform for intracellular drug delivery. Here we show the synthesis of functional supramolecular polymers by mixing of monomers with various functionalities. Introduction of cationic monomers made them suitable for cellular uptake and siRNA delivery.",

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Modular supramolecular ureidopyrimidinone polymer carriers for intracellular delivery

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