Modeling a heart pump

V. Creigen, L. Ferracina, A.V. Hlod, S. Mourik, van, K. Sjauw, V. Rottschäfer, M. Vellekoop, P.A. Zegeling

    Onderzoeksoutput: Hoofdstuk in Boek/Rapport/CongresprocedureConferentiebijdrageAcademicpeer review


    In patients with acute heart failure, the heart can be assisted by the insertion of a mechanical device which takes over part of the heart’s work load by pumping blood from the left ventricle, one of the heart chambers, into the aorta. In this project, we formulate a model that describes the effect of such a device on the cardiovascular dynamics. We show that data for the pressure–volume relationship within a heart chamber that have been obtained experimentally can be reproduced quite accurately by our model. Moreover, such experimental data can help in calibrating unknown parameters that specify the characteristics of the pump. A key parameter turned out to be the extra friction that is encountered by the blood flowing through the heart pump.
    Originele taal-2Engels
    TitelProceedings 58th European Study Group Mathematics with Industry (ESGI58/SWI2007), 29 January - 2 February 2007, Utrecht, The Netherlands
    RedacteurenR.H. Bisseling, K. Dajani, T.J. Dijkema, J. Leur, van de, P.A. Zegeling
    Plaats van productieUtrecht
    UitgeverijUtrecht University
    StatusGepubliceerd - 2007


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