Microfluidic actuation by modulation of surface stresses

A.A. Darhuber, J.P. Valentino, J.M. Davis, S.M. Troian, S. Wagner

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    Uittreksel

    We demonstrate the active manipulation of nanoliter liquid samples on the surface of a glass or silicon substrate by combining chemical surface patterning with electronically addressable microheater arrays. Hydrophilic lanes designate the possible routes for liquid migration while activation of specific heater elements determine the trajectories. The induced temperature fields spatially modulate the liquid surface tension thereby providing electronic control over the direction, timing, and flow rate of continuous streams or discrete drops. Temperature maps can be programed to move, split, trap, and mix ultrasmall volumes without mechanically moving parts and with low operating voltages of 2â€"3 V. This method of fluidic actuation allows direct accessibility to liquid samples for handling and diagnostic purposes and provides an attractive platform for palm-sized and battery-powered analysis and synthesis.
    Originele taal-2Engels
    Pagina's (van-tot)657-659
    Aantal pagina's3
    TijdschriftApplied Physics Letters
    Volume82
    Nummer van het tijdschrift4
    DOI's
    StatusGepubliceerd - 2003

    Vingerafdruk

    actuation
    modulation
    liquids
    liquid surfaces
    fluidics
    heaters
    electric batteries
    manipulators
    interfacial tension
    temperature distribution
    platforms
    flow velocity
    routes
    time measurement
    trajectories
    traps
    activation
    glass
    electric potential
    silicon

    Citeer dit

    Darhuber, A. A., Valentino, J. P., Davis, J. M., Troian, S. M., & Wagner, S. (2003). Microfluidic actuation by modulation of surface stresses. Applied Physics Letters, 82(4), 657-659. https://doi.org/10.1063/1.1537512
    Darhuber, A.A. ; Valentino, J.P. ; Davis, J.M. ; Troian, S.M. ; Wagner, S. / Microfluidic actuation by modulation of surface stresses. In: Applied Physics Letters. 2003 ; Vol. 82, Nr. 4. blz. 657-659.
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    abstract = "We demonstrate the active manipulation of nanoliter liquid samples on the surface of a glass or silicon substrate by combining chemical surface patterning with electronically addressable microheater arrays. Hydrophilic lanes designate the possible routes for liquid migration while activation of specific heater elements determine the trajectories. The induced temperature fields spatially modulate the liquid surface tension thereby providing electronic control over the direction, timing, and flow rate of continuous streams or discrete drops. Temperature maps can be programed to move, split, trap, and mix ultrasmall volumes without mechanically moving parts and with low operating voltages of 2{\^a}€{"}3 V. This method of fluidic actuation allows direct accessibility to liquid samples for handling and diagnostic purposes and provides an attractive platform for palm-sized and battery-powered analysis and synthesis.",
    author = "A.A. Darhuber and J.P. Valentino and J.M. Davis and S.M. Troian and S. Wagner",
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    Darhuber, AA, Valentino, JP, Davis, JM, Troian, SM & Wagner, S 2003, 'Microfluidic actuation by modulation of surface stresses', Applied Physics Letters, vol. 82, nr. 4, blz. 657-659. https://doi.org/10.1063/1.1537512

    Microfluidic actuation by modulation of surface stresses. / Darhuber, A.A.; Valentino, J.P.; Davis, J.M.; Troian, S.M.; Wagner, S.

    In: Applied Physics Letters, Vol. 82, Nr. 4, 2003, blz. 657-659.

    Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

    TY - JOUR

    T1 - Microfluidic actuation by modulation of surface stresses

    AU - Darhuber, A.A.

    AU - Valentino, J.P.

    AU - Davis, J.M.

    AU - Troian, S.M.

    AU - Wagner, S.

    PY - 2003

    Y1 - 2003

    N2 - We demonstrate the active manipulation of nanoliter liquid samples on the surface of a glass or silicon substrate by combining chemical surface patterning with electronically addressable microheater arrays. Hydrophilic lanes designate the possible routes for liquid migration while activation of specific heater elements determine the trajectories. The induced temperature fields spatially modulate the liquid surface tension thereby providing electronic control over the direction, timing, and flow rate of continuous streams or discrete drops. Temperature maps can be programed to move, split, trap, and mix ultrasmall volumes without mechanically moving parts and with low operating voltages of 2â€"3 V. This method of fluidic actuation allows direct accessibility to liquid samples for handling and diagnostic purposes and provides an attractive platform for palm-sized and battery-powered analysis and synthesis.

    AB - We demonstrate the active manipulation of nanoliter liquid samples on the surface of a glass or silicon substrate by combining chemical surface patterning with electronically addressable microheater arrays. Hydrophilic lanes designate the possible routes for liquid migration while activation of specific heater elements determine the trajectories. The induced temperature fields spatially modulate the liquid surface tension thereby providing electronic control over the direction, timing, and flow rate of continuous streams or discrete drops. Temperature maps can be programed to move, split, trap, and mix ultrasmall volumes without mechanically moving parts and with low operating voltages of 2â€"3 V. This method of fluidic actuation allows direct accessibility to liquid samples for handling and diagnostic purposes and provides an attractive platform for palm-sized and battery-powered analysis and synthesis.

    U2 - 10.1063/1.1537512

    DO - 10.1063/1.1537512

    M3 - Article

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    SP - 657

    EP - 659

    JO - Applied Physics Letters

    JF - Applied Physics Letters

    SN - 0003-6951

    IS - 4

    ER -