Maternal autonomic responsiveness is attenuated in healthy pregnancy: a phase rectified signal averaging analysis

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3 Citaten (Scopus)

Samenvatting

Autonomic regulation is essential in enabling a healthy pregnancy. In fact, several pregnancy complications are associated with autonomic dysfunction. Better understanding of the maternal autonomic state during healthy pregnancy may aid in the early detection of such complications. One aspect of autonomic regulation is autonomic responsiveness, which can by assessed by phase rectified signal averaging (PRSA). While other areas of research have found blunted physiological responses in pregnancy, this paper presents the first investigation of maternal autonomic responsiveness as assessed by PRSA. We find significantly reduced rates of responses, as well as an attenuated capacity for heart rate acceleration when comparing pregnant women to non-pregnant controls. We hypothesize that this attenuated autonomic control may serve to protect the mother against her imbalanced autonomic state, as increased sympathetic and decreased parasympathetic modulation accompany healthy pregnancies. Clinical Relevance - Maternal autonomic responsiveness is attenuated in pregnancy in comparison to non-pregnant women. Understanding maternal autonomic state not only improves our knowledge of gestational physiology but also forms the basis for the early detection of pregnancy complications associated with maternal autonomic dysfunction.

Originele taal-2Engels
Titel44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2022
UitgeverijInstitute of Electrical and Electronics Engineers
Pagina's4982-4986
Aantal pagina's5
ISBN van elektronische versie978-1-7281-2782-8
DOI's
StatusGepubliceerd - 8 sep. 2022
Evenement44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2022 - Scottish Event Campus, Glasgow, Verenigd Koninkrijk
Duur: 11 jul. 202215 jul. 2022
Congresnummer: 44

Congres

Congres44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2022
Verkorte titelEMBC 2022
Land/RegioVerenigd Koninkrijk
StadGlasgow
Periode11/07/2215/07/22

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