Managing trade-offs in protein manufacturing: how much to waste?

T.G. Martagan (Corresponding author), A. Krishnamurthy, P. Leland

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Samenvatting

We consider manufacturing trade-offs for engineer-to-order proteins. The biomanufacturer needs to determine how much protein to produce, and then how much of it to waste in subsequent operations because of the purity and yield trade-offs. We develop a Markov decision model, and determine structural characteristics of the optimal operating policies.
Originele taal-2Engels
Pagina's (van-tot)223-428
Aantal pagina's16
TijdschriftManufacturing & Service Operations Management
Volume22
Nummer van het tijdschrift2
DOI's
StatusGepubliceerd - 24 apr 2019

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065-1445

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