Managing trade-offs in protein manufacturing: how much to waste?

T.G. Martagan, A. Krishnamurthy, P. Leland

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

Uittreksel

We consider manufacturing trade-offs for engineer-to-order proteins. The biomanufacturer needs to determine how much protein to produce, and then how much of it to waste in subsequent operations because of the purity and yield trade-offs. We develop a Markov decision model, and determine structural characteristics of the optimal operating policies.
TaalEngels
TijdschriftManufacturing & Service Operations Management
DOI's
StatusGeaccepteerd/In druk - 2018

Vingerafdruk

Trade-offs
Manufacturing
Protein
Engineers
Decision model

Bibliografische nota

065-1445

Citeer dit

@article{063eb9251b2c43f9953fe846e807ee30,
title = "Managing trade-offs in protein manufacturing: how much to waste?",
abstract = "We consider manufacturing trade-offs for engineer-to-order proteins. The biomanufacturer needs to determine how much protein to produce, and then how much of it to waste in subsequent operations because of the purity and yield trade-offs. We develop a Markov decision model, and determine structural characteristics of the optimal operating policies.",
author = "T.G. Martagan and A. Krishnamurthy and P. Leland",
note = "065-1445",
year = "2018",
doi = "10.1287/msom.2018.0740",
language = "English",
journal = "Manufacturing & Service Operations Management",
issn = "1523-4614",
publisher = "INFORMS Institute for Operations Research and the Management Sciences",

}

Managing trade-offs in protein manufacturing: how much to waste? / Martagan, T.G.; Krishnamurthy, A.; Leland, P.

In: Manufacturing & Service Operations Management, 2018.

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

TY - JOUR

T1 - Managing trade-offs in protein manufacturing: how much to waste?

AU - Martagan,T.G.

AU - Krishnamurthy,A.

AU - Leland,P.

N1 - 065-1445

PY - 2018

Y1 - 2018

N2 - We consider manufacturing trade-offs for engineer-to-order proteins. The biomanufacturer needs to determine how much protein to produce, and then how much of it to waste in subsequent operations because of the purity and yield trade-offs. We develop a Markov decision model, and determine structural characteristics of the optimal operating policies.

AB - We consider manufacturing trade-offs for engineer-to-order proteins. The biomanufacturer needs to determine how much protein to produce, and then how much of it to waste in subsequent operations because of the purity and yield trade-offs. We develop a Markov decision model, and determine structural characteristics of the optimal operating policies.

U2 - 10.1287/msom.2018.0740

DO - 10.1287/msom.2018.0740

M3 - Article

JO - Manufacturing & Service Operations Management

T2 - Manufacturing & Service Operations Management

JF - Manufacturing & Service Operations Management

SN - 1523-4614

ER -