Systemic intermediaries play an important role in shaping socio-technical transitions. However, there is hardly any knowledge about contextual factors that enhance or inhibit systemic intermediary activities in transnational settings. This study draws on a case study of a European intermediary in the energy transition field. The intermediary has been active in both transition-progressive and less transition-oriented countries in Europe. In specific, we investigate the intermediary's activities in Sweden and Spain. Due to local factors, the intermediary's approach was difficult to realize in Sweden. Most activities were performed with niche-actors or universities only, undermining systemic intermediation. By contrast, Spanish local factors favored systemic intermediation, allowing the regime and niche levels to converge. The findings of the study extend the literature by showing why intermediation in transition-progressive regions can suffer and by highlighting that transnational intermediaries entering a transition-progressive region must account for the local intermediation ecology when defining their role.