Inflammation Mediated Fibrosis Is Regulated Through Distinct Gene-Gene Co-Expression Networks in the Failing Human Myocardium Before and After Left Ventricular Assist Device Support

V.K. Topkara; A. Godier-Furnemont; N. Bax; B. Fine; A. Garan; M. Yuzefpolskaya; K. Takeda; H. Takayama; Y. Naka; D. Mancini; P.C. Colombo; U.P. Jorde; G. Vunjak-Novakovic

doi:10.1016/j.healun.2015.01.582

Inflammation Mediated Fibrosis Is Regulated Through Distinct Gene-Gene Co-Expression Networks in the Failing Human Myocardium Before and After Left Ventricular Assist Device Support

V.K. Topkara
, A. Godier-Furnemont
, N. Bax
, B. Fine
, A. Garan
, M. Yuzefpolskaya
, K. Takeda
, H. Takayama
, Y. Naka
, D. Mancini
, P.C. Colombo
, U.P. Jorde
, G. Vunjak-Novakovic

Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review

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Sustained activation of pro-inflammatory signaling pathways leads to myocardial fibrosis and adverse left ventricular remodeling in mouse models of heart failure (HF). Regulatory genes/pathways responsible for inflammatory-mediated fibrosis in human HF are not well established.

Originele taal-2	Engels
Artikelnummer	S212
Aantal pagina's	1
Tijdschrift	Journal of Heart and Lung Transplantation
Volume	34
Nummer van het tijdschrift	4
DOI's	https://doi.org/10.1016/j.healun.2015.01.582
Status	Gepubliceerd - apr 2015
Extern gepubliceerd	Ja

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10.1016/j.healun.2015.01.582Licentie: Onbepaald

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Topkara, V. K., Godier-Furnemont, A., Bax, N., Fine, B., Garan, A., Yuzefpolskaya, M., Takeda, K., Takayama, H., Naka, Y., Mancini, D., Colombo, P. C., Jorde, U. P., & Vunjak-Novakovic, G. (2015). Inflammation Mediated Fibrosis Is Regulated Through Distinct Gene-Gene Co-Expression Networks in the Failing Human Myocardium Before and After Left Ventricular Assist Device Support. Journal of Heart and Lung Transplantation, 34(4), Artikel S212. https://doi.org/10.1016/j.healun.2015.01.582

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title = "Inflammation Mediated Fibrosis Is Regulated Through Distinct Gene-Gene Co-Expression Networks in the Failing Human Myocardium Before and After Left Ventricular Assist Device Support",

abstract = "Sustained activation of pro-inflammatory signaling pathways leads to myocardial fibrosis and adverse left ventricular remodeling in mouse models of heart failure (HF). Regulatory genes/pathways responsible for inflammatory-mediated fibrosis in human HF are not well established.",

author = "V.K. Topkara and A. Godier-Furnemont and N. Bax and B. Fine and A. Garan and M. Yuzefpolskaya and K. Takeda and H. Takayama and Y. Naka and D. Mancini and P.C. Colombo and U.P. Jorde and G. Vunjak-Novakovic",

year = "2015",

month = apr,

doi = "10.1016/j.healun.2015.01.582",

language = "English",

volume = "34",

journal = "Journal of Heart and Lung Transplantation",

issn = "1053-2498",

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Topkara, VK, Godier-Furnemont, A, Bax, N, Fine, B, Garan, A, Yuzefpolskaya, M, Takeda, K, Takayama, H, Naka, Y, Mancini, D, Colombo, PC, Jorde, UP & Vunjak-Novakovic, G 2015, 'Inflammation Mediated Fibrosis Is Regulated Through Distinct Gene-Gene Co-Expression Networks in the Failing Human Myocardium Before and After Left Ventricular Assist Device Support', Journal of Heart and Lung Transplantation, vol. 34, nr. 4, S212. https://doi.org/10.1016/j.healun.2015.01.582

Inflammation Mediated Fibrosis Is Regulated Through Distinct Gene-Gene Co-Expression Networks in the Failing Human Myocardium Before and After Left Ventricular Assist Device Support. / Topkara, V.K.; Godier-Furnemont, A.; Bax, N. et al.
In: Journal of Heart and Lung Transplantation, Vol. 34, Nr. 4, S212, 04.2015.

Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review

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T1 - Inflammation Mediated Fibrosis Is Regulated Through Distinct Gene-Gene Co-Expression Networks in the Failing Human Myocardium Before and After Left Ventricular Assist Device Support

AU - Topkara, V.K.

AU - Godier-Furnemont, A.

AU - Bax, N.

AU - Fine, B.

AU - Garan, A.

AU - Yuzefpolskaya, M.

AU - Takeda, K.

AU - Takayama, H.

AU - Naka, Y.

AU - Mancini, D.

AU - Colombo, P.C.

AU - Jorde, U.P.

AU - Vunjak-Novakovic, G.

PY - 2015/4

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N2 - Sustained activation of pro-inflammatory signaling pathways leads to myocardial fibrosis and adverse left ventricular remodeling in mouse models of heart failure (HF). Regulatory genes/pathways responsible for inflammatory-mediated fibrosis in human HF are not well established.

AB - Sustained activation of pro-inflammatory signaling pathways leads to myocardial fibrosis and adverse left ventricular remodeling in mouse models of heart failure (HF). Regulatory genes/pathways responsible for inflammatory-mediated fibrosis in human HF are not well established.

U2 - 10.1016/j.healun.2015.01.582

DO - 10.1016/j.healun.2015.01.582

M3 - Article

SN - 1053-2498

VL - 34

JO - Journal of Heart and Lung Transplantation

JF - Journal of Heart and Lung Transplantation

IS - 4

M1 - S212

ER -

Inflammation Mediated Fibrosis Is Regulated Through Distinct Gene-Gene Co-Expression Networks in the Failing Human Myocardium Before and After Left Ventricular Assist Device Support

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