Inferring a third spatial dimension from 2D histological images

Maxime W. Lafarge; Josien P.W. Pluim; Koen A.J. Eppenhof; Pim Moeskops; Mitko Veta

doi:10.1109/ISBI.2018.8363644

Inferring a third spatial dimension from 2D histological images

Maxime W. Lafarge, Josien P.W. Pluim, Koen A.J. Eppenhof, Pim Moeskops, Mitko Veta

Medical Image Analysis

Onderzoeksoutput: Hoofdstuk in Boek/Rapport/Congresprocedure › Conferentiebijdrage › Academic › peer review

1 Citaat (Scopus)

Samenvatting

Histological images are obtained by transmitting light through a tissue specimen that has been stained in order to produce contrast. This process results in 2D images of the specimen that has a three-dimensional structure. In this paper, we propose a method to infer how the stains are distributed in the direction perpendicular to the surface of the slide for a given 2D image in order to obtain a 3D representation of the tissue. This inference is achieved by decomposition of the staining concentration maps under constraints that ensure realistic decomposition and reconstruction of the original 2D images. Our study shows that it is possible to generate realistic 3D images making this method a potential tool for data augmentation when training deep learning models.

Originele taal-2	Engels
Titel	2018 IEEE 15th International Symposium on Biomedical Imaging, ISBI 2018
Plaats van productie	Piscataway
Uitgeverij	IEEE Computer Society
Pagina's	586-589
Aantal pagina's	4
Volume	2018-April
ISBN van elektronische versie	978-1-5386-3636-7
ISBN van geprinte versie	978-1-5386-3637-4
DOI's	https://doi.org/10.1109/ISBI.2018.8363644
Status	Gepubliceerd - 23 mei 2018
Evenement	15th IEEE International Symposium on Biomedical Imaging (ISBI 2018) - Omni Shoreham Hotel, Washington, Verenigde Staten van Amerika Duur: 4 apr 2018 → 7 apr 2018 Congresnummer: 15 https://biomedicalimaging.org/2018/

Congres

Congres	15th IEEE International Symposium on Biomedical Imaging (ISBI 2018)
Verkorte titel	ISBI18
Land	Verenigde Staten van Amerika
Stad	Washington
Periode	4/04/18 → 7/04/18
Internet adres	https://biomedicalimaging.org/2018/

Toegang tot document

10.1109/ISBI.2018.8363644

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Citeer dit

Lafarge, M. W., Pluim, J. P. W., Eppenhof, K. A. J., Moeskops, P., & Veta, M. (2018). Inferring a third spatial dimension from 2D histological images. In 2018 IEEE 15th International Symposium on Biomedical Imaging, ISBI 2018 (Vol. 2018-April, blz. 586-589). IEEE Computer Society. https://doi.org/10.1109/ISBI.2018.8363644

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title = "Inferring a third spatial dimension from 2D histological images",

abstract = "Histological images are obtained by transmitting light through a tissue specimen that has been stained in order to produce contrast. This process results in 2D images of the specimen that has a three-dimensional structure. In this paper, we propose a method to infer how the stains are distributed in the direction perpendicular to the surface of the slide for a given 2D image in order to obtain a 3D representation of the tissue. This inference is achieved by decomposition of the staining concentration maps under constraints that ensure realistic decomposition and reconstruction of the original 2D images. Our study shows that it is possible to generate realistic 3D images making this method a potential tool for data augmentation when training deep learning models.",

keywords = "3D Inference, Adversarial Training, Histopathology Image Analysis, Image Synthesis",

author = "Lafarge, {Maxime W.} and Pluim, {Josien P.W.} and Eppenhof, {Koen A.J.} and Pim Moeskops and Mitko Veta",

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Lafarge, MW , Pluim, JPW, Eppenhof, KAJ, Moeskops, P & Veta, M 2018, Inferring a third spatial dimension from 2D histological images. in 2018 IEEE 15th International Symposium on Biomedical Imaging, ISBI 2018. vol. 2018-April, IEEE Computer Society, Piscataway, blz. 586-589, 15th IEEE International Symposium on Biomedical Imaging (ISBI 2018), Washington, Verenigde Staten van Amerika, 4/04/18. https://doi.org/10.1109/ISBI.2018.8363644

Inferring a third spatial dimension from 2D histological images. / Lafarge, Maxime W.; Pluim, Josien P.W.; Eppenhof, Koen A.J.; Moeskops, Pim; Veta, Mitko.

2018 IEEE 15th International Symposium on Biomedical Imaging, ISBI 2018. Vol. 2018-April Piscataway : IEEE Computer Society, 2018. blz. 586-589.

Onderzoeksoutput: Hoofdstuk in Boek/Rapport/Congresprocedure › Conferentiebijdrage › Academic › peer review

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