Impact of Additives on Mechanical Properties of Supramolecular Electrospun Scaffolds

Bastiaan D Ippel; Eline E Van Haaften; Carlijn V C Bouten; Patricia Y W Dankers

doi:10.1021/acsapm.0c00658

Impact of Additives on Mechanical Properties of Supramolecular Electrospun Scaffolds

Bastiaan D Ippel, Eline E Van Haaften, Carlijn V C Bouten, Patricia Y W Dankers (Corresponding author)

Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review

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The mechanical properties of scaffolds used for mechanically challenging applications such as cardiovascular implants are unequivocally important. Here, the effect of supramolecular additive functionalization on mechanical behavior of electrospun scaffolds was investigated for one bisurea-based model additive and two previously developed antifouling additives. The model additive has no effect on the mechanical properties of the bulk material, whereas the stiffness of electrospun scaffolds was slightly decreased compared to pristine PCL-BU following the addition of the three different additives. These results show the robustness of supramolecular additives used in biomedical applications, in which mechanical properties are important, such as vascular grafts and heart valve constructs.

Originele taal-2	Engels
Pagina's (van-tot)	3742-3748
Aantal pagina's	7
Tijdschrift	ACS Applied Polymer Materials
Volume	2
Nummer van het tijdschrift	9
DOI's	https://doi.org/10.1021/acsapm.0c00658
Status	Gepubliceerd - 11 sep. 2020

Bibliografische nota

Financiering

This work was funded by the European Research Council (FP7/2007–2013) ERC Grant Agreement No. 308045, the Ministry of Education, Culture and Science (Gravity Program 024.001.035), and ZonMW as part of the LSH 2Treat program (Project No. 436001003).

Financiers	Financiernummer
Seventh Framework Programme
European Research Council	308045
ZonMw : Dutch Organisation for Health Research and Development	436001003
Ministerie van OCW	024.001.035

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Impact of Additives on Mechanical Properties of Supramolecular Electrospun Scaffolds

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