Imaging the ultrasonic coefficient of nonlinearity: The impact of speed of sound variations

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Imaging the acoustical coefficient of nonlinearity, β, is of interest in a number of healthcare interventional applications. For cardiac ablation therapy, detecting the protective fibrofatty layer between the atrial wall and the esophagus would provide risk assessment with respect to esophageal injury. The coefficient of nonlinearity β is an important feature that can be used for discriminating between tissues. Starting from a 1D inhomogeneous generalized lossy nonlinear Westervelt equation, we derived an analytical solution for β, which is then further adapted to work in echo mode. By considering the ratio between the harmonic and fundamental fields, the influence of spatial variations in backscatter coefficient and spatial absorption variations are mitigated. By testing the method on simulations that range from a 1D plane wave excitation with inhomogeneous nonlinearity and absorption, to a 3D linear array scan that also considers inhomogeneities in speed of sound, we show that the designed algorithm is able to estimate the coefficient of nonlinearity, and that the tissue types of interest are well discriminable. The proposed imaging method provides a new approach to β estimation, not requiring a special measurement setup or transducer, that seems particularly promising for in vivo imaging.
Originele taal-2Engels
TitelInternational Ultrasonics Symposium IEEE, Taipei, Taiwan, 2015
Plaats van productiePiscataway
UitgeverijInstitute of Electrical and Electronics Engineers
ISBN van elektronische versie978-1-4799-8182-3
DOI's
StatusGepubliceerd - 2015
Evenement2015 IEEE International Ultrasonics Symposium (IUS 2015) - Taipei International Convention Center, Taipei, Taiwan
Duur: 21 okt 201524 okt 2015
http://ewh.ieee.org/conf/ius/ius_2015/

Congres

Congres2015 IEEE International Ultrasonics Symposium (IUS 2015)
Verkorte titel2015 IUS
LandTaiwan
StadTaipei
Periode21/10/1524/10/15
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  • Citeer dit

    van Sloun, R. J., Demi, L., Shan, C., & Mischi, M. (2015). Imaging the ultrasonic coefficient of nonlinearity: The impact of speed of sound variations. In International Ultrasonics Symposium IEEE, Taipei, Taiwan, 2015 Institute of Electrical and Electronics Engineers. https://doi.org/10.1109/ULTSYM.2015.0243