Imaging-guided nanomedicine development

Aurora Bernal, Claudia Calcagno, Willem J.M. Mulder, Carlos Pérez-Medina (Corresponding author)

Onderzoeksoutput: Bijdrage aan tijdschriftArtikel recenserenpeer review

Samenvatting

Nanomedicine research is an active field that produces thousands of studies every year. However, translation of nanotherapeutics to the clinic has yet to catch up with such a vast output. In recent years, the need to better understand nanomedicines’ in vivo behavior has been identified as one of the major challenges for efficient clinical translation. In this context, noninvasive imaging offers attractive solutions to provide valuable information about nanomedicine biodistribution, pharmacokinetics, stability, or therapeutic efficacy. Here, we review the latest imaging approaches used in the development of therapeutic nanomedicines, discuss why these strategies bring added value along the translational pipeline, and give a perspective on future advances in the field.

Originele taal-2Engels
Pagina's (van-tot)78-85
Aantal pagina's8
TijdschriftCurrent Opinion in Chemical Biology
Volume63
DOI's
StatusGepubliceerd - aug 2021

Bibliografische nota

Publisher Copyright:
© 2021 Elsevier Ltd

Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.

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