Hypoxia affects mesenchymal stromal cell osteogenic differentiation and angiogenic factor expression

E. Potier; E. Ferreira; R. Andriamanalijaona; J.P. Pujol; K. Oudina; D. Logeart-Avramoglou; H. Petite

doi:10.1016/j.bone.2006.11.024

Hypoxia affects mesenchymal stromal cell osteogenic differentiation and angiogenic factor expression

E. Potier
, E. Ferreira
, R. Andriamanalijaona
, J.P. Pujol
, K. Oudina
, D. Logeart-Avramoglou
, H. Petite

Orthopaedic Biomechanics

Onderzoeksoutput: Bijdrage aan tijdschrift › Tijdschriftartikel › Academic › peer review

260 Citaten (Scopus)

Samenvatting

Mesenchymal stromal cells (MSCs) seeded onto biocompatible scaffolds have been proposed for repairing bone defects. When transplanted in vivo, MSCs (expanded in vitro in 21% O(2)) undergo temporary oxygen deprivation due to the lack of pre-existing blood vessels within these scaffolds. In the present study, the effects of temporary (48 h) exposure to hypoxia (

Originele taal-2	Engels
Pagina's (van-tot)	1078-87
Tijdschrift	Bone
Volume	40
Nummer van het tijdschrift	4
DOI's	https://doi.org/10.1016/j.bone.2006.11.024
Status	Gepubliceerd - 2007

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title = "Hypoxia affects mesenchymal stromal cell osteogenic differentiation and angiogenic factor expression",

abstract = "Mesenchymal stromal cells (MSCs) seeded onto biocompatible scaffolds have been proposed for repairing bone defects. When transplanted in vivo, MSCs (expanded in vitro in 21\% O(2)) undergo temporary oxygen deprivation due to the lack of pre-existing blood vessels within these scaffolds. In the present study, the effects of temporary (48 h) exposure to hypoxia (",

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AU - Potier, E.

AU - Ferreira, E.

AU - Andriamanalijaona, R.

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AU - Oudina, K.

AU - Logeart-Avramoglou, D.

AU - Petite, H.

PY - 2007

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AB - Mesenchymal stromal cells (MSCs) seeded onto biocompatible scaffolds have been proposed for repairing bone defects. When transplanted in vivo, MSCs (expanded in vitro in 21% O(2)) undergo temporary oxygen deprivation due to the lack of pre-existing blood vessels within these scaffolds. In the present study, the effects of temporary (48 h) exposure to hypoxia (

U2 - 10.1016/j.bone.2006.11.024

DO - 10.1016/j.bone.2006.11.024

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JO - Bone

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Hypoxia affects mesenchymal stromal cell osteogenic differentiation and angiogenic factor expression

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