How to distinguish isodesmic from cooperative supramolecular polymerisation

M.M.J. Smulders, M.M.L. Nieuwenhuizen, T.F.A. Greef, de, Paul Schoot, van der, A.P.H.J. Schenning, E.W. Meijer

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

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Samenvatting

To study the supramolecular polymerisation mechanisms of a self-assembling system, concentration- and temperature-dependent measurements can both be used to probe the transition from the molecular dissolved state to the aggregated state. In this report, both methods are evaluated to determine their effectiveness in identifying and quantifying the self-assembly mechanism for isodesmic and cooperative self-assembling systems. It was found that for a rapid and unambiguous determination of the self-assembly mechanism and its thermodynamic parameters, temperature-dependent measurements are more appropriate. These studies allow the acquisition of a large data set leading to an accurate determination of the self-assembly mechanism and quantification of the different thermodynamic parameters that describe the supramolecular polymerisation. For a comprehensive characterisation, additional concentration-dependent measurements can be performed.
Originele taal-2Engels
Pagina's (van-tot)362-367
TijdschriftChemistry : A European Journal
Volume16
Nummer van het tijdschrift1
DOI's
StatusGepubliceerd - 2010

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