Functionalization of protein-based nanocages for drug delivery applications

L. Schoonen, J.C.M. van Hest

Onderzoeksoutput: Bijdrage aan tijdschriftArtikel recenserenpeer review

137 Citaten (Scopus)


Traditional drug delivery strategies involve drugs which are not targeted towards the desired tissue. This can lead to undesired side effects, as normal cells are affected by the drugs as well. Therefore, new systems are now being developed which combine targeting functionalities with encapsulation of drug cargo. Protein nanocages are highly promising drug delivery platforms due to their perfectly defined structures, biocompatibility, biodegradability and low toxicity. A variety of protein nanocages have been modified and functionalized for these types of applications. In this review, we aim to give an overview of different types of modifications of protein-based nanocontainers for drug delivery applications.

Originele taal-2Engels
Pagina's (van-tot)7124-7141
Aantal pagina's18
Nummer van het tijdschrift13
StatusGepubliceerd - 7 jul. 2014
Extern gepubliceerdJa


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