Fast biosensor with reagent layer

A detection system and a sensor chip for detecting target mols., and thus corresponding analytes in a sample is described. Typically the detection system includes a sensor chip. The sensor chip (1) comprises on its detection surface a dissolvable reagent layer. When the dissolvable reagent layer is in contact with sample fluid, free reagent is generated, assisting in the interaction between a label and target mols., thus allowing for label based detection. The sample thereby is exposed to mobile reagents in a burst. The reagent layer may contain an enzyme allowing enzymic assays. [on SciFinder (R)]