Enhanced selectivity for the hydrolysis of block copoly(2-oxazoline)s in ethanol-water resulting in linear poly(ethylene imine) copolymers

H.P.C. Kuringen, van, V.R. Rosa, de la, M.W.M. Fijten, J.P.A. Heuts, R. Hoogenboom

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

22 Citaten (Scopus)
2 Downloads (Pure)

Samenvatting

The ability of merging the properties of poly(2-oxazoline)s and poly(ethylene imine) is of high interest for various biomedical applications, including gene delivery, biosensors, and switchable surfaces and nanoparticles. In the present research, a methodology for the controlled and selective hydrolysis of (co)poly(2-oxazoline)s is developed in an ethanol–water solvent mixture, opening the path toward a wide range of block poly(2-oxazoline-co-ethylene imine) (POx-PEI) copolymers with tunable properties. The unexpected influence of the selected ethanol–water binary solvent mixture on the hydrolysis kinetics and selectivity is highlighted in the pursue of well-defined POx-PEI block copolymers
Originele taal-2Engels
Pagina's (van-tot)827-832
Aantal pagina's6
TijdschriftMacromolecular Rapid Communications
Volume33
Nummer van het tijdschrift9
DOI's
StatusGepubliceerd - 2012

Vingerafdruk

Duik in de onderzoeksthema's van 'Enhanced selectivity for the hydrolysis of block copoly(2-oxazoline)s in ethanol-water resulting in linear poly(ethylene imine) copolymers'. Samen vormen ze een unieke vingerafdruk.

Citeer dit