Enhanced cell–chip coupling by rapid femtosecond laser patterning of soft PEDOT:PSS biointerfaces

F. Santoro, Y. van de Burgt, S.T. Keene, B. Cui, A. Salleo

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

5 Citaties (Scopus)

Uittreksel

Interfacing soft materials with biological systems holds considerable promise for both biosensors and recording live cells. However, the interface between cells and organic substrates is not well studied, despite its crucial role in the effectiveness of the device. Furthermore, well-known cell adhesion enhancers, such as microgrooves, have not been implemented on these surfaces. Here, we present a nanoscale characterization of the cell–substrate interface for 3D laser-patterned organic electrodes by combining electrochemical impedance spectroscopy (EIS) and scanning electron microscopy/focused ion beam (SEM/FIB). We demonstrate that introducing 3D micropatterned grooves on organic surfaces enhances the cell adhesion of electrogenic cells.
TaalEngels
Pagina's39116-39121
TijdschriftACS Applied Materials & Interfaces
Volume9
Nummer van het tijdschrift45
DOI's
StatusGepubliceerd - 30 okt 2017

Vingerafdruk

Cell adhesion
Ultrashort pulses
Organic lasers
Focused ion beams
Biological systems
Substrates
Electrochemical impedance spectroscopy
Biosensors
Cells
Scanning electron microscopy
Electrodes
poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate)

Citeer dit

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abstract = "Interfacing soft materials with biological systems holds considerable promise for both biosensors and recording live cells. However, the interface between cells and organic substrates is not well studied, despite its crucial role in the effectiveness of the device. Furthermore, well-known cell adhesion enhancers, such as microgrooves, have not been implemented on these surfaces. Here, we present a nanoscale characterization of the cell–substrate interface for 3D laser-patterned organic electrodes by combining electrochemical impedance spectroscopy (EIS) and scanning electron microscopy/focused ion beam (SEM/FIB). We demonstrate that introducing 3D micropatterned grooves on organic surfaces enhances the cell adhesion of electrogenic cells.",
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Enhanced cell–chip coupling by rapid femtosecond laser patterning of soft PEDOT:PSS biointerfaces. / Santoro, F.; van de Burgt, Y.; Keene, S.T.; Cui, B.; Salleo, A.

In: ACS Applied Materials & Interfaces, Vol. 9, Nr. 45, 30.10.2017, blz. 39116-39121.

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

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AU - Santoro,F.

AU - van de Burgt,Y.

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AU - Cui,B.

AU - Salleo,A.

PY - 2017/10/30

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