Drug delivery through microneedles

Onderzoeksoutput: Hoofdstuk in Boek/Rapport/CongresprocedureHoofdstukAcademicpeer review

1 Citaat (Scopus)
2 Downloads (Pure)

Uittreksel

Drug delivery through microneedles is a new form of a pharmaceutical dosage system. While single microneedles have been clinically applied already, the out-of-plane integration of a multitude of microneedles in a pharmaceutical patch is a disruptive technology. To take advantage of micro- and nanofluidics, such active patches utilize microneedle array (MNA) technology. MNAs are microsystems that adopt their technical uniqueness by the choice of a fabrication technology. MNAs can be made of solid, hollow, porous, or dissolvable materials in a cost-effective manner by the so-called MEMS technology. However, key to their success will be a proof-of-concept in the clinic, which must demonstrate that the intradermal (nano)release of drugs and vaccines serve an unmet medical need. In this chapter, we discuss recently established MNA platform technologies and by means of a case study we assess novel opportunities for MNAs in drug and vaccine delivery arising from this novel skin interface.

Originele taal-2Engels
TitelMicrosystems for Pharmatechnology : Manipulation of Fluids, Particles, Droplets, and Cells
RedacteurenA. Dietzel
Plaats van productieDordrecht
UitgeverijSpringer
Pagina's275-298
Aantal pagina's24
ISBN van geprinte versie9783319269207, 9783319269184
DOI's
StatusGepubliceerd - 1 jan 2016

Vingerafdruk

Drug delivery
Technology
Pharmaceutical Preparations
Vaccines
Drug products
Micro-Electrical-Mechanical Systems
Nanofluidics
Microfluidics
Microsystems
MEMS
Skin
Costs and Cost Analysis
Fabrication
Costs

Citeer dit

Luttge, R. (2016). Drug delivery through microneedles. In A. Dietzel (editor), Microsystems for Pharmatechnology : Manipulation of Fluids, Particles, Droplets, and Cells (blz. 275-298). Dordrecht: Springer. https://doi.org/10.1007/978-3-319-26920-7_10
Luttge, R. / Drug delivery through microneedles. Microsystems for Pharmatechnology : Manipulation of Fluids, Particles, Droplets, and Cells. redacteur / A. Dietzel. Dordrecht : Springer, 2016. blz. 275-298
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Luttge, R 2016, Drug delivery through microneedles. in A Dietzel (redactie), Microsystems for Pharmatechnology : Manipulation of Fluids, Particles, Droplets, and Cells. Springer, Dordrecht, blz. 275-298. https://doi.org/10.1007/978-3-319-26920-7_10

Drug delivery through microneedles. / Luttge, R.

Microsystems for Pharmatechnology : Manipulation of Fluids, Particles, Droplets, and Cells. redactie / A. Dietzel. Dordrecht : Springer, 2016. blz. 275-298.

Onderzoeksoutput: Hoofdstuk in Boek/Rapport/CongresprocedureHoofdstukAcademicpeer review

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Luttge R. Drug delivery through microneedles. In Dietzel A, redacteur, Microsystems for Pharmatechnology : Manipulation of Fluids, Particles, Droplets, and Cells. Dordrecht: Springer. 2016. blz. 275-298 https://doi.org/10.1007/978-3-319-26920-7_10