Double solenoid ELF in vitro exposure system with high homogeneity and small stray field

Concerning in-vitro biological studies, it is necessary that a well-characterized exposure system is used particularly to validate and replicate key findings. Therefore, we improved and characterized an ELF magnetic field exposure system with high dynamic exposure range (µT–mT) and reduced stray magnetic fields for a 50/60Hz sinusoidal signal. The basic design is based on a double solenoid setup. The outer solenoid is used for the reduction of the stray B-flux densities. The system itself is modular to adapt to different biological experiments. To be able to apply a high dynamic exposure range a controlled air cooling system is added. The exposure system is using a control algorithm and associated Graphical User Interface. Temperature is measured and controlled inside the exposure area. The exposure characteristics along with temperature variation are monitored and recorded during the experiments. In conclusion, the ELF exposure system is well suited to conduct a wide range of real and sham ELF magnetic field cell-exposure studies.