TY - JOUR
T1 - Development and validation of novel imaging technologies to assist translational studies in atherosclerosis
AU - Miserus, R.J.H.M.
AU - Heeneman, S.
AU - Engelshoven, van, J.M.A.
AU - Kooi, M.E.
AU - Daemen, M.J.A.P.
PY - 2006
Y1 - 2006
N2 - In the past decade, significant progress has been made to visualize atherosclerotic disease. Until recently, imaging technologies mainly focused on lumen and vessel wall visualization. Current advances and knowledge on the molecular mechanisms of initiation and progression of atherosclerosis has emphasized the need for imaging technologies and probes that can image function and biology rather than anatomy. This field of molecular imaging is now in rapid development with new imaging agents that aim at visualizing processes involved in atherosclerosis such as inflammation, macrophage activation, protease activity, angiogenesis, apoptosis, lipid accumulation and thrombus formation. © 2006 Elsevier Ltd. All rights reserved.
AB - In the past decade, significant progress has been made to visualize atherosclerotic disease. Until recently, imaging technologies mainly focused on lumen and vessel wall visualization. Current advances and knowledge on the molecular mechanisms of initiation and progression of atherosclerosis has emphasized the need for imaging technologies and probes that can image function and biology rather than anatomy. This field of molecular imaging is now in rapid development with new imaging agents that aim at visualizing processes involved in atherosclerosis such as inflammation, macrophage activation, protease activity, angiogenesis, apoptosis, lipid accumulation and thrombus formation. © 2006 Elsevier Ltd. All rights reserved.
U2 - 10.1016/j.ddtec.2006.06.008
DO - 10.1016/j.ddtec.2006.06.008
M3 - Article
C2 - 24980408
SN - 1740-6749
VL - 3
SP - 195
EP - 204
JO - Drug Discovery Today: Technologies
JF - Drug Discovery Today: Technologies
IS - 2
ER -