COVID-19 during pregnancy: non-reassuring fetal heart rate, placental pathology and coagulopathy

J E Mongula, M W E Frenken (Corresponding author), G van Lijnschoten, N L A Arents, L D de Wit-Zuurendonk, A P A Schimmel-de Kok, P J van Runnard Heimel, M M Porath, S M T A Goossens

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

Samenvatting

A case of a pregnant woman suffering from COVID-19 is presented, who developed coagulopathy in the absence of severe clinical symptoms. The PCR test of the vaginal swab was positive on SARS-CoV-2 RNA, suggesting a possibility of perinatal transmission. A cesarean delivery was done because of a non-reassuring fetal heart rate; the placenta showed increased perivillous fibrin deposition and intervillositis. Moreover, placental infection with SARS-CoV-2 was demonstrated by placental immunostaining. We suggest a relation between placental fibrin deposition and both chronic and acute intervillositis, non-reassuring fetal heart rate and coagulopathy in pregnant women with COVID-19. This article is protected by copyright. All rights reserved.

Originele taal-2Engels
TijdschriftUltrasound in Obstetrics and Gynecology
DOI's
StatusE-publicatie vóór gedrukte publicatie - 27 aug 2020

Bibliografische nota

This article is protected by copyright. All rights reserved.

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    Perinatal Medicine

    M.B. (Beatrijs) van der Hout-van der Jagt (Content manager) & Eugenie Delvaux (Content manager)

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