Controlling internal pore sizes in bicontinuous polymeric nanospheres

B.E. McKenzie, H. Friedrich, M.J.M. Wirix, J.F. de Visser, P. Monaghan, P.H.H. Bomans, F. Nudelman, S.J. Holder, N.A.J.M. Sommerdijk

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Samenvatting

Complex polymeric nanospheres were formed in water from comb-like amphiphilic block copolymers. Their internal morphology was determined by three-dimensional cryo-electron tomographic analysis. Varying the polymer molecular weight (MW) and the hydrophilic block weight content allowed for fine control over the internal structure. Construction of a partial phase diagram allowed us to determine the criteria for the formation of bicontinuous polymer nanosphere (BPN), namely for copolymers with MW of up to 17 kDa and hydrophilic weight fractions of =0.25; and varying the organic solvent to water ratio used in their preparation allowed for control over nanosphere diameters from 70 to 460 nm. Significantly, altering the block copolymer hydrophilic–hydrophobic balance enabled control of the internal pore diameter of the BPNs from 10 to 19 nm.
Originele taal-2Engels
Pagina's (van-tot)2457-2461
TijdschriftAngewandte Chemie - International Edition
Volume54
Nummer van het tijdschrift8
DOI's
StatusGepubliceerd - 16 feb 2015

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  • Uitrusting

    Center for Multiscale Electron Microscopy (CMEM)

    Heiner Friedrich (Manager), Rick Joosten (Gebruiker), Demi de Moor (Gebruiker), Pauline Schmit (Gebruiker), Ingeborg Schreur - Piet (Gebruiker), Anne Spoelstra (Gebruiker) & Nina Romme - van Moll (Inhoud)

    Materials and Interface Chemistry

    Uitrusting/faciliteit: Onderzoekslaboratorium

  • Citeer dit

    McKenzie, B. E., Friedrich, H., Wirix, M. J. M., de Visser, J. F., Monaghan, P., Bomans, P. H. H., Nudelman, F., Holder, S. J., & Sommerdijk, N. A. J. M. (2015). Controlling internal pore sizes in bicontinuous polymeric nanospheres. Angewandte Chemie - International Edition, 54(8), 2457-2461. https://doi.org/10.1002/anie.201408811