Consequences of folding a water-soluble polymer around an organocatalyst

E. Huerta Martinez, P.J.M. Stals, E.W. Meijer, A.R.A. Palmans

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Uittreksel

Give 'em structure: The presence of structuring elements in polymers that were functionalized with catalytic units resulted in a new class of enzyme mimics, which are only active in the folded state (see picture). The conformationally adaptive hydrophobic environment that surrounds the catalytic site allows the very efficient catalysis of an aldol reaction in water with Michaelis–Menten kinetics.
TaalEngels
Pagina's2906-2910
Aantal pagina's5
TijdschriftAngewandte Chemie - International Edition
Volume52
Nummer van het tijdschrift10
DOI's
StatusGepubliceerd - 2013

Vingerafdruk

Catalysis
Polymers
Enzymes
Kinetics
Water
3-hydroxybutanal

Citeer dit

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Consequences of folding a water-soluble polymer around an organocatalyst. / Huerta Martinez, E.; Stals, P.J.M.; Meijer, E.W.; Palmans, A.R.A.

In: Angewandte Chemie - International Edition, Vol. 52, Nr. 10, 2013, blz. 2906-2910.

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

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