TY - JOUR
T1 - Consequences of cooperativity in racemizing supramolecular systems
AU - Cantekin, S.
AU - Eikelder, ten, H.M.M.
AU - Markvoort, A.J.
AU - Veld, M.A.J.
AU - Korevaar, P.A.
AU - Green, M.M.
AU - Palmans, A.R.A.
AU - Meijer, E.W.
PY - 2012
Y1 - 2012
N2 - Saluting the sergeant: Phg-BTA cooperatively self-assembles into helical aggregates and shows unprecedented racemization behavior in the presence of base. In thermodynamically controlled conditions, the addition of a small amount of chiral auxiliary to this mixture results in a deracemization reaction and a final enantiomeric excess of 32¿%. A theoretical model is presented to understand in detail the results obtained.
AB - Saluting the sergeant: Phg-BTA cooperatively self-assembles into helical aggregates and shows unprecedented racemization behavior in the presence of base. In thermodynamically controlled conditions, the addition of a small amount of chiral auxiliary to this mixture results in a deracemization reaction and a final enantiomeric excess of 32¿%. A theoretical model is presented to understand in detail the results obtained.
U2 - 10.1002/anie.201201701
DO - 10.1002/anie.201201701
M3 - Article
C2 - 22593079
SN - 0570-0833
VL - 51
SP - 6426
EP - 6431
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
IS - 26
ER -