TY - JOUR
T1 - Congenital epulis of the jaw
T2 - a series of five cases and review of literature
AU - Küpers, A. Marlijn
AU - Andriessen, Peter
AU - van Kempen, Muriel J.P.
AU - van der Tol, Ignaz G.H.
AU - Baart, Jacques A.
AU - Dumans, Antoine G.
AU - van der Waal, Isaäc
PY - 2009/2
Y1 - 2009/2
N2 - This article describes five cases of congenital epulis, a rare and benign swelling in the mouth of a newborn, which is not widely known. We present five cases: four cases presented as single pedunculated nodules of the gingiva and in one case two nodules were present. Of all, 50% were located at the maxilla. Excision was performed in four of the five cases and in one case, spontaneous regression was awaited. No recurrence was reported. The characteristic features of congenital epulis are a pedunculated, flesh-pink coloured tumour with a predominant occurrence on the anterior maxillary alveolar ridge in a female newborn. Although the aetiology is unknown, most authors suggest a mesenchymal, rather than an odontogenic, origin. Endogenous hormonal factors might influence growth prenatally. Histological findings include granular cells with eosinophilic cytoplasm and small, eccentric nuclei. Despite the fact that the lesion can be a striking sight, spontaneous regression is possible and can be awaited. Indications for non-radical excision under local anaesthesia are severe upper airway obstruction and interference with feeding technique. In conclusion, we provide clinical and histological information about congenital epulis, so that this entity will be more easily recognised and relevant information given to parents.
AB - This article describes five cases of congenital epulis, a rare and benign swelling in the mouth of a newborn, which is not widely known. We present five cases: four cases presented as single pedunculated nodules of the gingiva and in one case two nodules were present. Of all, 50% were located at the maxilla. Excision was performed in four of the five cases and in one case, spontaneous regression was awaited. No recurrence was reported. The characteristic features of congenital epulis are a pedunculated, flesh-pink coloured tumour with a predominant occurrence on the anterior maxillary alveolar ridge in a female newborn. Although the aetiology is unknown, most authors suggest a mesenchymal, rather than an odontogenic, origin. Endogenous hormonal factors might influence growth prenatally. Histological findings include granular cells with eosinophilic cytoplasm and small, eccentric nuclei. Despite the fact that the lesion can be a striking sight, spontaneous regression is possible and can be awaited. Indications for non-radical excision under local anaesthesia are severe upper airway obstruction and interference with feeding technique. In conclusion, we provide clinical and histological information about congenital epulis, so that this entity will be more easily recognised and relevant information given to parents.
KW - Female
KW - Gingival Neoplasms/congenital
KW - Humans
KW - Infant, Newborn
KW - Jaw Neoplasms/congenital
KW - Remission, Spontaneous
U2 - 10.1007/s00383-008-2304-8
DO - 10.1007/s00383-008-2304-8
M3 - Review article
C2 - 19082830
SN - 0179-0358
VL - 25
SP - 207
EP - 210
JO - Pediatric Surgery International
JF - Pediatric Surgery International
IS - 2
ER -