Computational modeling of braided venous stents - effect of design features and device-tissue interaction on stent performance

R.L.J.M. Ubachs, Olaf van der Sluis (Corresponding author), Scott Smith, Jake Mertens

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

2 Citaten (Scopus)
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Samenvatting

Designing venous stents with desired properties is challenging due to the partly conflicting performance criteria, e.g., enhancing flexibility may be at odds with increasing patency. To evaluate the effect of design parameters on the mechanical performance of
braided stents, computational simulations are performed using finite element analysis. Model validation is performed through comparison with measurements. Considered design features are stent length, wire diameter, pick rate, number of wires, and stent
end-type, being either open-ended or closed looped. Based on the requirements of venous stents, tests are defined to study the effect of design variations with respect to the following key performance criteria: chronic outward force, crush resistance, conformability, and foreshortening. Computational modeling is demonstrated to be a valuable tool in the design process through its ability of assessing sensitivities of various performance metrics to the design parameters. Additionally, it is shown, using computational modeling, that the interaction between a braided stent and its surrounding anatomy has a significant impact on its performance. Therefore, taking into account device-tissue interaction is crucial for the proper assessment of stent performance.
Originele taal-2Engels
Artikelnummer105857
Aantal pagina's15
TijdschriftJournal of the Mechanical Behavior of Biomedical Materials
Volume142
DOI's
StatusGepubliceerd - jun. 2023

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