Chelating amphiphilic polymers

Holger Gruell; Anke de Vries; Sander Langereis; Johan Lub; Erica M.G. Aussems-Custers

Chelating amphiphilic polymers

Holger Gruell (Uitvinder), Anke de Vries (Uitvinder), Sander Langereis (Uitvinder), Johan Lub (Uitvinder), Erica M.G. Aussems-Custers (Uitvinder)

Onderzoeksoutput: Octrooi › Octrooi-publicatie

47 Downloads (Pure)

Samenvatting

Described are amphiphilic polymers that are provided with chelating moieties. The amphiphilic polymers are block copolymers comprising a hydrophilic block and a hydrophobic block, with the chelating moieties linked to the end-group of the hydrophilic block. The disclosed polymers are capable of self-assembly into structures such as micelles and polymersomes. With suitable metals present in the form of coordination complexes with 5 the chelating moieties, the chelating amphiphilic polymers of the invention are suitable for use in various imaging techniques requiring metal labeling, such as MRI (T 1/T 2 weighted contrast agents or CEST contrast agents) SPECT, PET or Spectral CT.

Originele taal-2	Engels
Octrooinummer	US2011165074
IPC	C08F 8/ 32 A I
Prioriteitsdatum	8/09/09
Status	Gepubliceerd - 7 jul. 2011

Toegang tot document

US2011165074A1Definitieve gepubliceerde versie, 1,78 MB

https://nl.espacenet.com/publicationDetails/biblio?II=0&ND=3&adjacent=true&locale=nl_NL&FT=D&date=20110707&CC=US&NR=2011165074A1&KC=A1#

Citeer dit

@misc{3b229cbc52944b16b8625ff6d3d209ff,

title = "Chelating amphiphilic polymers",

abstract = "Described are amphiphilic polymers that are provided with chelating moieties. The amphiphilic polymers are block copolymers comprising a hydrophilic block and a hydrophobic block, with the chelating moieties linked to the end-group of the hydrophilic block. The disclosed polymers are capable of self-assembly into structures such as micelles and polymersomes. With suitable metals present in the form of coordination complexes with 5 the chelating moieties, the chelating amphiphilic polymers of the invention are suitable for use in various imaging techniques requiring metal labeling, such as MRI (T 1/T 2 weighted contrast agents or CEST contrast agents) SPECT, PET or Spectral CT.",

author = "Holger Gruell and {de Vries}, Anke and Sander Langereis and Johan Lub and Aussems-Custers, {Erica M.G.}",

year = "2011",

month = jul,

day = "7",

language = "English",

type = "Patent",

note = "US2011165074; C08F 8/ 32 A I",

}

TY - PAT

T1 - Chelating amphiphilic polymers

AU - Gruell, Holger

AU - de Vries, Anke

AU - Langereis, Sander

AU - Lub, Johan

AU - Aussems-Custers, Erica M.G.

PY - 2011/7/7

Y1 - 2011/7/7

N2 - Described are amphiphilic polymers that are provided with chelating moieties. The amphiphilic polymers are block copolymers comprising a hydrophilic block and a hydrophobic block, with the chelating moieties linked to the end-group of the hydrophilic block. The disclosed polymers are capable of self-assembly into structures such as micelles and polymersomes. With suitable metals present in the form of coordination complexes with 5 the chelating moieties, the chelating amphiphilic polymers of the invention are suitable for use in various imaging techniques requiring metal labeling, such as MRI (T 1/T 2 weighted contrast agents or CEST contrast agents) SPECT, PET or Spectral CT.

AB - Described are amphiphilic polymers that are provided with chelating moieties. The amphiphilic polymers are block copolymers comprising a hydrophilic block and a hydrophobic block, with the chelating moieties linked to the end-group of the hydrophilic block. The disclosed polymers are capable of self-assembly into structures such as micelles and polymersomes. With suitable metals present in the form of coordination complexes with 5 the chelating moieties, the chelating amphiphilic polymers of the invention are suitable for use in various imaging techniques requiring metal labeling, such as MRI (T 1/T 2 weighted contrast agents or CEST contrast agents) SPECT, PET or Spectral CT.

M3 - Patent publication

M1 - US2011165074

ER -

Chelating amphiphilic polymers

Samenvatting

Toegang tot document

Vingerafdruk

Citeer dit