Samenvatting
A binuclear fused 5-membered palladacycle (2) and a palladium complex of amido-functionalized N-heterocyclic carbene (6) successfully performed the Csp2−Csp type Hiyama coupling followed by cyclization giving the biologically important benzofuran compounds in a convenient time economic method involving one-pot tandem reaction between 2-iodophenol and triethoxysilylalkynes. The aromatic triethoxysilylalkyne substrates exhibited higher yields than the aliphatic triethoxysilylalkyne substrates for both of the palladium complexes 2 (ca. 19−48%) and 6 (ca. 11−34%). The binuclear fused 5-membered palladacycle (2) was readily synthesized by the nucleophilic addition of 2-amino-pyridine on the cis-{(2,4,6-(CH3)3C6H2)NC}2PdCl2 in good yield (ca. 74%) and the palladium complex of amido-functionalized N-heterocyclic carbene (6) was synthesized by transmetallation route from the silver complex (5) with (COD)PdCl2 in CH3CN under reflux condition in ca. 38% of yield.
| Originele taal-2 | Engels |
|---|---|
| Pagina's (van-tot) | 9361-9367 |
| Aantal pagina's | 7 |
| Tijdschrift | ChemistrySelect |
| Volume | 3 |
| Nummer van het tijdschrift | 32 |
| DOI's | |
| Status | Gepubliceerd - 31 aug. 2018 |
| Extern gepubliceerd | Ja |
Bibliografische nota
Publisher Copyright:© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
Financiering
We thank the Department of Science and Technology (EMR/2014/000254), New Delhi, India, and Council of Scientific & Industrial Research (CSIR) {01(2880)/17/EMR-II} New Delhi, India, for financial support of this research. We gratefully acknowledge Single Crystal X-ray Diffraction Facility, Department of Chemistry, IIT Bombay, Mumbai, India, for the crystallographic characterization data. C.S., A.P.P. and M.K.G., thank CSIR, New Delhi, India, for research fellowships.