An environmentally benign and selective electrochemical oxidation of sulfides and thiols in a continuous-flow microreactor

G. Laudadio, N.J.W. Straathof, M.D. Lanting, B. Knoops, V. Hessel, T. Noël

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

44 Citaten (Scopus)
148 Downloads (Pure)

Samenvatting

A practical and environmentally benign electrochemical oxidation of thioethers and thiols in a commercially-available continuous-flow microreactor is presented. Water is used as the source of oxygen to enable the oxidation process. The oxidation reaction utilizes the same reagents in all scenarios and the selectivity is solely governed by the applied potential. The procedure exhibits a broad scope and good functional group compatibility providing access to various sulfoxides (15 examples), sulfones (15 examples) and disulfides (6 examples). The use of continuous flow allows the optimal reaction parameters (e.g. residence time, applied voltage) to be rapidly assessed, to avoid mass- and heat-transfer limitations and to scale the electrochemistry.
Originele taal-2Engels
Pagina's (van-tot)4061-4066
Aantal pagina's6
TijdschriftGreen Chemistry
Volume19
Nummer van het tijdschrift17
DOI's
StatusGepubliceerd - 7 aug 2017

Vingerafdruk Duik in de onderzoeksthema's van 'An environmentally benign and selective electrochemical oxidation of sulfides and thiols in a continuous-flow microreactor'. Samen vormen ze een unieke vingerafdruk.

  • Citeer dit