A numerical model to predict abdominal aortic aneurysm expansion based on local wall stress and stiffness

F. Helderman, I.J. Manoch, M. Breeuwer, U. Kose, O. Schouten, M.R.H.M. Sambeek, van, D. Poldermans, T.M. Pattynama, W. Wisselink, A.F.W. Steen, van der, R. Krams

Onderzoeksoutput: Bijdrage aan tijdschriftTijdschriftartikelAcademicpeer review

16 Citaten (Scopus)

Samenvatting

Aneurysms of the abdominal aorta enlarge until rupture occurs. We assume that this is the result of remodelling to restore wall stress. We developed a numerical model to predict aneurysm expansion based on this assumption. In addition, we obtained aneurysm geometry of 11 patients from computed tomography angiographic images to obtain patient specific calculations. The assumption of a wall stress related expansion indeed resulted in a series of local expansions, adjusting global geometry in an exponential fashion similar as in patients. Furthermore, it revealed that location of peak wall stress changed over time. The assumptions of this model are discussed in detail in this manuscript, and the implications are related to literature findings.
Originele taal-2Engels
Pagina's (van-tot)1121-1127
Aantal pagina's7
TijdschriftMedical and Biological Engineering and Computing
Volume46
Nummer van het tijdschrift11
DOI's
StatusGepubliceerd - 2008
Extern gepubliceerdJa

Vingerafdruk Duik in de onderzoeksthema's van 'A numerical model to predict abdominal aortic aneurysm expansion based on local wall stress and stiffness'. Samen vormen ze een unieke vingerafdruk.

Citeer dit